Orathecin
National Institutes of Health
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Purpose: The purpose of this phase II study was to evaluate the efficacy and tolerability of Orathecin, an oral camptothecin…
4165 Background: Rubitecan (Orathecin) is a novel oral inhibitor of topoisomerase I in the camptothecin class. Methods: A Phase…
The FDA has made great strides over the past twenty years in loosening drug approval regulations to speed important, life-saving…
Rubitecan [Orathecin, 9-nitrocamptothecin, 9NC, RFS 2000] is a topoisomerase I inhibitor extracted from the bark and leaves of…
2106 Background: 9NC (Orathecin) is an orally administered camptothecin analogue that has completed phase III trials for…