Optic vesicle

One of two small outpouchings formed from the evagination of the optic groove during early eye formation in the developing embryo.
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Differentiation methods for human induced pluripotent stem cells (hiPSCs) typically yield progeny from multiple tissue lineages… (More)
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Review
2010
Review
2010
Organogenesis of the eye is a multistep process that starts with the formation of optic vesicles followed by invagination of the… (More)
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Highly Cited
2006
Highly Cited
2006
The cellular mechanisms underlying organ formation are largely unknown. We visualized early vertebrate eye morphogenesis at… (More)
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Highly Cited
2003
Highly Cited
2003
During early formation of the eye, the optic vesicle becomes partitioned into a proximal domain that forms the optic nerve and a… (More)
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Highly Cited
2000
Highly Cited
2000
The vertebrate eye develops from the neuroepithelium of the ventral forebrain by the evagination and formation of the optic… (More)
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Highly Cited
2000
Highly Cited
2000
The use of genetics to study the development of the telencephalon and derivatives such as the cerebral cortex has been limited… (More)
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Highly Cited
2000
Highly Cited
2000
The Pax6 transcription factor plays a key role in ocular development of vertebrates and invertebrates. Homozygosity of the Pax6… (More)
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Highly Cited
1998
Highly Cited
1998
Patterning of the bipotential retinal primordia (the optic vesicles) into neural retina and retinal pigmented epithelium depends… (More)
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Highly Cited
1997
Highly Cited
1997
We investigated the function of Lhx2, a LIM homeobox gene expressed in developing B-cells, forebrain and neural retina, by… (More)
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Highly Cited
1995
Highly Cited
1995
Small eye (Sey) mice homozygous for mutations in the Pax-6 gene have no lenses and no nasal cavities. We have examined the… (More)
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