• Publications
  • Influence
Establishment in culture of pluripotential cells from mouse embryos
The establishment in tissue culture of pluripotent cell lines which have been isolated directly from in vitro cultures of mouse blastocysts are reported, able to differentiate either in vitro or after innoculation into a mouse as a tumour in vivo. Expand
The Atlas of Mouse Development
Assessment of Developmental Stage of Pre- and Postimplantation Mouse Embryos Based on the Staging System of Theiler (1989) and general Observations on the Urogenital Ridges, Gonads, and Genital Duct System. Expand
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
The results of blastocyst injection studies using three independently isolated XY embryo-derived cell lines, which produce a very high proportion of live-born animals that are overtly chimaeric, are reported. Expand
The embryology of conjoined twins
  • M. Kaufman
  • Biology, Medicine
  • Child's Nervous System
  • 27 July 2004
Conjoined twinning occurs by the incomplete splitting of the embryonic axis and, with the exception of parasitic conjoined twins, all are symmetrical and “the same parts are always united to the same parts”. Expand
High-frequency developmental abnormalities in p53-deficient mice
It is reported that a significant proportion of female p53-/- mice die during embryogenesis or in the period between birth and weaning, being subject to a spectrum of abnormalities. Expand
Classification of Proliferative Pulmonary Lesions of the Mouse
A series of discussions was initiated by a panel of human, veterinary, and experimental pathologists during the Mouse Models of Human Cancers Consortium (NIH/National Cancer Institute) workshop on mouse models of lung cancer, and a new practical classification scheme was recommended that would allow easier comparison between human and mouse lung neoplasms. Expand
Eyelid development, fusion and subsequent reopening in the mouse.
The process of eyelid development was studied in the mouse. The critical events occur between about 15.5 d postcoitum (p.c.) and 12 d after birth, and were studied by conventional histology and byExpand
The prion protein gene: a role in mouse embryogenesis?
The neural membrane glycoprotein PrP (prion protein) has a key role in the development of scrapie and related neurodegenerative diseases. During pathogenesis, PrP accumulates in and around cells ofExpand
High-resolution magnetic resonance histology of the embryonic and neonatal mouse: A 4D atlas and morphologic database
An integrated environment for high-resolution study of normal, transgenic, and mutant mouse models at embryonic and neonatal stages with carefully annotated normative data and an extensive environment for collaborations is described. Expand
Corneal abnormalities in Pax6+/- small eye mice mimic human aniridia-related keratopathy.
Investigating corneal abnormalities in heterozygous Pax6(+/Sey-Neu) (Pax6 (+/-), small eye) mice and comparing them with aniridia-related keratopathy in PAX 6(+/-) patients extends the relevance of this mouse model of humanAniridia to include corneals abnormalities. Expand