Optic Atrophy, Hereditary, Leber

Known as: Leber's optic atrophy, Optic Neuroretinopathy, Hereditary, Optic Atrophy, Leber, Hereditary 
A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Leber's hereditary optic neuropathy, the most frequent mitochondrial disease due to mitochondrial DNA point mutations in complex… (More)
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Review
2011
Review
2011
Leber hereditary optic neuropathy (LHON) and autosomal-dominant optic atrophy (DOA) are the two most common inherited optic… (More)
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Review
2009
Review
2009
Leber hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (DOA) are the two most common inherited optic… (More)
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Highly Cited
2009
Highly Cited
2009
Leber hereditary optic neuropathy (LHON) is a genetic disorder primarily due to mutations of mitochondrial DNA (mtDNA… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE To study retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (StratusOCT) in patients with Leber's… (More)
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Review
2004
Review
2004
Mitochondria are increasingly recognized as central players in the life and death of cells and especially of neurons. The energy… (More)
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Highly Cited
2000
Highly Cited
2000
Leber's hereditary optic neuropathy (LHON) is a form of blindness caused by mitochondrial DNA (mtDNA) mutations in complex I… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Leber's hereditary neuropathy of the optic nerve (LHON) is manifested by bilateral affection of the eyes with acute or… (More)
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Highly Cited
1994
Highly Cited
1994
A five-generation Hispanic family expressing maternally transmitted Leber hereditary optic neuropathy and/or early-onset dystonia… (More)
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Highly Cited
1992
Highly Cited
1992
Eight women are described who presented with bilateral, usually sequential, optic neuropathy, six of whom later developed a… (More)
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