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Olfactomedin-4

Known as: Antiapoptotic Protein GW112, G-CSF-Stimulated Clone 1 Protein, bA209J19.1 
Olfactomedin-4 (510 aa, ~57 kDa) is encoded by the human OLFM4 gene. This protein is involved in regulation of apoptosis.
National Institutes of Health

Related topics

Related topics

4 relations
ApoptosisGenes, RegulatorOLFM4 generegulatory proteins

Papers overview

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2018
2018
Marked differences in tight junction composition and macromolecular permeability among different intestinal cell types
BackgroundMammalian small intestinal tight junctions (TJ) link epithelial cells to one another and function as a permselective… Expand
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2017
2017
Olfactomedin-4 Is a Candidate Marker for a Pathogenic Neutrophil Subset in Septic Shock
Objectives: Heterogeneity in sepsis-related pathobiology presents a significant challenge. Resolving this heterogeneity presents… Expand
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Highly Cited
2016
Highly Cited
2016
The alterations in the extracellular matrix composition guide the repair of damaged liver tissue
While the cellular mechanisms of liver regeneration have been thoroughly studied, the role of extracellular matrix (ECM) in liver… Expand
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2015
2015
Olfactomedin 4 Serves as a Marker for Disease Severity in Pediatric Respiratory Syncytial Virus (RSV) Infection
Background Respiratory viral infections follow an unpredictable clinical course in young children ranging from a common cold to… Expand
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2015
2015
Olfactomedin-4 autoantibodies give unusual c-ANCA staining patterns with reactivity to a subpopulation of neutrophils.
Testing for the presence of ANCAs in circulation is part of the clinical examinations routinely performed upon suspected… Expand
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2014
2014
Robust Cre-Mediated Recombination in Small Intestinal Stem Cells Utilizing the Olfm4 Locus
Summary The epithelium of the small intestine is the most rapidly self-renewing tissue in mammals. We previously demonstrated the… Expand
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2012
2012
Olfactomedin-4 is a glycoprotein secreted into mucus in active IBD.
BACKGROUND Olfactomedin-4 (OLFM4) is a glycoprotein characteristic of intestinal stem cells and apparently involved in mucosal… Expand
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Highly Cited
2011
Highly Cited
2011
A Quantitative Proteomic Approach of the Different Stages of Colorectal Cancer Establishes OLFM4 as a New Nonmetastatic Tumor Marker*
Expression profiles represent new molecular tools that are useful to characterize the successive steps of tumor progression and… Expand
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2011
2011
Role of proteomics to differentiate between benign and potentially malignant pancreatic cysts.
Pancreatic cystic neoplasms represent 10-15% of primary cystic masses of the pancreas. While pancreatic cysts are detected with… Expand
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2010
2010
Olfactomedin-4 regulation by estrogen in the human endometrium requires epidermal growth factor signaling.
Olfactomedin-4 (OLFM-4) is an extracellular matrix protein that is highly expressed in human endometrium. We have examined the… Expand
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