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OSW 1

Known as: 3 beta, 16 beta, 17-alpha-trihydroxy-cholest-5-en-22-one 16-O-(2-O-4-methoxybenzoyl-beta-D-xylopyranosyl)- (1-->3)-(2-O-acetyl-alpha-L-arabinopyranoside), OSW-1 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Saponins

Papers overview

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2017
2017
Uncovering oxysterol‐binding protein (OSBP) as a target of the anti‐enteroviral compound TTP‐8307
Highly Cited
2017
Highly Cited
2017
Sterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP
The network of proteins that orchestrate the distribution of cholesterol among cellular organelles is not fully characterized. We… 
Highly Cited
2015
Highly Cited
2015
Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein
Highly Cited
2011
Highly Cited
2011
FYX-051: A Novel and Potent Hybrid-Type Inhibitor of Xanthine Oxidoreductase
4-[5-(Pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile (FYX-051) is a potent inhibitor of bovine milk xanthine… 
2009
2009
Synthesis of 3beta, 7alpha, 11alpha-trihydroxy-pregn-21-benzylidene-5-en-20-one derivatives and their cytotoxic activities.
Highly Cited
2005
Highly Cited
2005
OSW-1: a natural compound with potent anticancer activity and a novel mechanism of action.
The naturally occurring compound 3beta,16beta,17alpha-trihydroxycholest-5-en-22-one 16-O-(2-O-4-methoxybenzoyl-beta-D… 
Highly Cited
2002
Highly Cited
2002
Total synthesis of the anticancer natural product OSW-1.
The highly potent anticancer natural saponin OSW-1 has been successfully synthesized from commercially available 5-androsten… 
Highly Cited
2001
Highly Cited
2001
Structure of Green Pigment Formed by the Reaction of Caffeic Acid Esters (or Chlorogenic acid) with a Primary Amino Compound
A marked greening observed in some foods such as sweet potato, burdock, and others during food processing was shown to be due to… 
Highly Cited
1999
Highly Cited
1999
First Total Synthesis of an Exceptionally Potent Antitumor Saponin, OSW-1.
OSW-1 (1), an acylated disaccharide cholestane saponin from Ornithogalum saudersiae with exceptionally potent antitumor activity… 
Highly Cited
1997
Highly Cited
1997
Inhibitory effect of a new steroidal saponin, OSW‐1, on ovarian functions in rats
1 This study was undertaken to determine the effects of OSW‐1 (3β, 16β, 17α‐trihydroxycholest‐5‐en‐22‐one 16‐O‐(2‐O‐4… 
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