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OSMR protein, human

Known as: IL-31R Subunit Beta, Oncostatin-M Specific Receptor Beta Subunit, OSMR 
Oncostatin-M-specific receptor subunit beta (979 aa, ~111 kDa) is encoded by the human OSMR gene. This protein plays a role in interleukin-31 and… Expand
National Institutes of Health

Related topics

Related topics

16 relations
Cell ProliferationCytokine Receptor GeneCytokine Signaling ProcessIntegral Membrane Proteins
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Broader (1)

Oncostatin-M Specific Receptor Beta Subunit

Papers overview

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Highly Cited
2015
Highly Cited
2015
Oncostatin m, an inflammatory cytokine produced by macrophages, supports intramembranous bone healing in a mouse model of tibia injury.
Different macrophage depletion strategies have demonstrated a vital role of macrophages in bone healing, but the underlying… Expand
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2015
2015
Analysis of IL-6/gp130 family receptor expression reveals that in contrast to astroglia, microglia lack the oncostatin M receptor and functional responses to oncostatin M.
The interleukin (IL)-6/gp130 family of cytokines (e.g., IL-6, IL-11, leukemia inhibitory factor (LIF) and oncostatin M (OSM… Expand
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2013
2013
Lack of Oncostatin M Receptor β Leads to Adipose Tissue Inflammation and Insulin Resistance by Switching Macrophage Phenotype*
Background: OSM, a member of IL-6 family of cytokines, is involved in many inflammatory diseases. Results: OSMRβ−/− mice… Expand
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Highly Cited
2010
Highly Cited
2010
Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice.
Effective osteoporosis therapy requires agents that increase the amount and/or quality of bone. Any modification of osteoclast… Expand
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Highly Cited
2006
Highly Cited
2006
Complete overlap of interleukin-31 receptor A and oncostatin M receptor β in the adult dorsal root ganglia with distinct developmental expression patterns
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor… Expand
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Highly Cited
2003
Highly Cited
2003
Targeted disruption of oncostatin M receptor results in altered hematopoiesis.
Oncostatin M (OSM) is a multifunctional cytokine that belongs to the interleukin 6 (IL-6) family. As OSM is expressed in adult as… Expand
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Highly Cited
2002
Highly Cited
2002
Novel Role of Janus Kinase 1 in the Regulation of Oncostatin M Receptor Surface Expression*
The oncostatin M receptor (OSMR) is part of a heterodimeric receptor complex that mediates signal transduction of the pleiotropic… Expand
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2000
2000
Non-redundant Signal Transduction of Interleukin-6-type Cytokines
The common use of the cytokine receptor gp130 has served as an explanation for the extremely redundant biological activities… Expand
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1999
1999
Induction of Low Density Lipoprotein Receptor (LDLR) Transcription by Oncostatin M Is Mediated by the Extracellular Signal-regulated Kinase Signaling Pathway and the Repeat 3 Element of the LDLR…
Oncostatin M (OM) activates the transcription of the human low density lipoprotein receptor (LDLR) in HepG2 cells through a… Expand
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Highly Cited
1989
Highly Cited
1989
Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M.
Oncostatin M is a polypeptide of Mr approximately 28,000 that acts as a growth regulator for many cultured mammalian cells. We… Expand
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