Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

OSMR protein, human

Known as: IL-31R Subunit Beta, Oncostatin-M Specific Receptor Beta Subunit, OSMR 
Oncostatin-M-specific receptor subunit beta (979 aa, ~111 kDa) is encoded by the human OSMR gene. This protein plays a role in interleukin-31 and… Expand
National Institutes of Health

Related topics

Related topics

16 relations
Cell ProliferationCytokine Receptor GeneCytokine Signaling ProcessIntegral Membrane Proteins
Expand

Broader (1)

Oncostatin-M Specific Receptor Beta Subunit

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Analysis of IL‐6/gp130 family receptor expression reveals that in contrast to astroglia, microglia lack the oncostatin M receptor and functional responses to oncostatin M
The interleukin (IL)‐6/gp130 family of cytokines (e.g., IL‐6, IL‐11, leukemia inhibitory factor (LIF) and oncostatin M (OSM… Expand
Highly Cited
2015
Highly Cited
2015
Oncostatin m, an inflammatory cytokine produced by macrophages, supports intramembranous bone healing in a mouse model of tibia injury.
Different macrophage depletion strategies have demonstrated a vital role of macrophages in bone healing, but the underlying… Expand
Highly Cited
2010
Highly Cited
2010
Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice.
Effective osteoporosis therapy requires agents that increase the amount and/or quality of bone. Any modification of osteoclast… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Review
2008
Review
2008
Structures and biological functions of IL-31 and IL-31 receptors.
Interleukin-31, produced mainly by activated CD4(+) T cells, is a newly discovered member of the gp130/IL-6 cytokine family… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2003
Highly Cited
2003
Targeted disruption of oncostatin M receptor results in altered hematopoiesis.
Oncostatin M (OSM) is a multifunctional cytokine that belongs to the interleukin 6 (IL-6) family. As OSM is expressed in adult as… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Highly Cited
2002
Highly Cited
2002
Novel Role of Janus Kinase 1 in the Regulation of Oncostatin M Receptor Surface Expression*
The oncostatin M receptor (OSMR) is part of a heterodimeric receptor complex that mediates signal transduction of the pleiotropic… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2000
Highly Cited
2000
Non-redundant Signal Transduction of Interleukin-6-type Cytokines
The common use of the cytokine receptor gp130 has served as an explanation for the extremely redundant biological activities… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
1999
Highly Cited
1999
Induction of Low Density Lipoprotein Receptor (LDLR) Transcription by Oncostatin M Is Mediated by the Extracellular Signal-regulated Kinase Signaling Pathway and the Repeat 3 Element of the LDLR…
Oncostatin M (OM) activates the transcription of the human low density lipoprotein receptor (LDLR) in HepG2 cells through a… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Highly Cited
1991
Highly Cited
1991
Oncostatin M up-regulates low density lipoprotein receptors in HepG2 cells by a novel mechanism.
Oncostatin M is a growth regulatory protein secreted by macrophages and activated T lymphocytes. In a hepatoma cell line (HepG2… Expand
Highly Cited
1989
Highly Cited
1989
Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M.
Oncostatin M is a polypeptide of Mr approximately 28,000 that acts as a growth regulator for many cultured mammalian cells. We… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE