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ORF74 protein, Human herpesvirus 8

Known as: ORF-74 protein, HHV-8, Protein ORF74, Putative G-Protein Coupled Receptor 
Viral G-protein coupled receptor (342 aa, ~39 kDa) is encoded by the human herpesvirus 8 ORF74 gene. This protein plays a role in the positive… 
National Institutes of Health

Related topics

Related topics

9 relations
Cell Migration InductionGenes, ViralHHV8 ORF74 GenePositive Regulation of Angiogenesis

Broader (2)

Viral Proteinschemokine receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Ligand-selective small molecule modulators of the constitutively active vGPCR US28.
2015
2015
Glycosylation of KSHV Encoded vGPCR Functions in Its Signaling and Tumorigenicity
Kaposi’s sarcoma-associated herpesvirus (KSHV) is a tumor virus and the etiologic agent of Kaposi’s Sarcoma (KS). KSHV G protein… 
2013
2013
Kaposi sarcoma-associated herpesvirus g protein-coupled receptor enhances endothelial cell survival in part by upregulation of bcl-2.
BACKGROUND Kaposi sarcoma-associated herpesvirus (KSHV) encoded G protein-coupled receptor (vGPCR) is a constitutively active… 
2012
2012
Kaposi's Sarcoma-Associated Herpesvirus G-Protein-Coupled Receptor Prevents AU-Rich-Element-Mediated mRNA Decay
ABSTRACT During lytic Kaposi's sarcoma-associated herpesvirus (KSHV) infection, host gene expression is severely restricted by a… 
2009
2009
Kaposi's sarcoma virally encoded, G-protein-coupled receptor: a paradigm for paracrine transformation.
2008
2008
Kaposi's Sarcoma-Associated Herpesvirus K7 Induces Viral G Protein-Coupled Receptor Degradation and Reduces Its Tumorigenicity
The Kaposi's sarcoma-associated herpesvirus (KSHV) genome encodes a G protein-coupled receptor (vGPCR). vGPCR is a ligand… 
2007
2007
The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells
Review
2007
Review
2007
Investigational agents for treatment of AIDS-related Kaposi’s sarcoma
AIDS-related Kaposi’s sarcoma (KS) is a neoplasm that results from the co-infection of HIV and KS herpesvirus/human herpesvirus-8… 
Review
2006
Review
2006
Emerging targets and novel strategies in the treatment of AIDS‐related Kaposi's sarcoma: Bidirectional translational science
Through the mentorship process, Dr. Arthur Pardee emphasized the critical importance of bidirectional translational research—not… 
2005
2005
Splicing of Rhesus Rhadinovirus R15 and ORF74 Bicistronic Transcripts during Lytic Infection and Analysis of Effects on Production of vCD200 and vGPCR
ABSTRACT Rhesus macaque rhadinovirus (RRV) is the rhesus macaque homologue of human herpesvirus 8 (HHV-8). Here we examine… 
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