OPC 14597

Known as: 14597, OPC, OPC-14597 
 
National Institutes of Health

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Broader (1)

aripiprazole

Papers overview

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Highly Cited
2014
Highly Cited
2014
Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522.
PURPOSE Combining cisplatin or cetuximab with radiation improves overall survival (OS) of patients with stage III or IV head and… (More)
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Highly Cited
2013
Highly Cited
2013
Dynamic Service Provisioning in Elastic Optical Networks With Hybrid Single-/Multi-Path Routing
Empowered by the optical orthogonal frequency-division multiplexing (O-OFDM) technology, flexible online service provisioning can… (More)
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Highly Cited
2011
Highly Cited
2011
Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial.
BACKGROUND The association between human papillomavirus (HPV) and overall survival (OS) in oropharynx cancer (OPC) was… (More)
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Highly Cited
2010
Highly Cited
2010
Transplanted Oligodendrocytes and Motoneuron Progenitors Generated from Human Embryonic Stem Cells Promote Locomotor Recovery After Spinal Cord Transection
Human embryonic stem cells (hESC) hold great promise for the treatment of patients with many neurodegenerative diseases… (More)
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Highly Cited
2010
Highly Cited
2010
Transplantation of ciliary neurotrophic factor-expressing adult oligodendrocyte precursor cells promotes remyelination and functional recovery after spinal cord injury.
Demyelination contributes to the dysfunction after traumatic spinal cord injury (SCI). We explored whether the combination of… (More)
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Highly Cited
2009
Highly Cited
2009
Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation.
Although both extrinsic and intrinsic factors have been identified that orchestrate the differentiation and maturation of… (More)
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2008
2008
Effects of aripiprazole/OPC-14597 on motor activity, pharmacological models of psychosis, and brain activity in rats
Aripiprazole (OPC-14597) is an antipsychotic with a unique pharmacology as a dopamine D2 receptor partial agonist, which has been… (More)
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Highly Cited
2003
Highly Cited
2003
Aripiprazole, A Novel Atypical Antipsychotic Drug with a Unique and Robust Pharmacology
Atypical antipsychotic drugs have revolutionized the treatment of schizophrenia and related disorders. The current clinically… (More)
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Highly Cited
1999
Highly Cited
1999
Interactions of the Novel Antipsychotic Aripiprazole (OPC-14597) with Dopamine and Serotonin Receptor Subtypes
OPC-14597 {aripiprazole; 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone} is a novel candidate… (More)
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1995
1995
Behavioural and neurochemical effects of OPC-14597, a novel antipsychotic drug, on dopaminergic mechanisms in rat brain
OPC-14597 is a new antipsychotic drug with a unique pharmacological profile. In a behavioural study in rats OPC-14597 did not… (More)
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