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OPC-14523

Known as: PRS-013 
 
National Institutes of Health

Papers overview

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2007
2007
OPC-14523 (OPC) is a novel compound with high affinity for sigma and 5-HT1A receptors that shows ‘antidepressant-like’ effects in… Expand
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2005
2005
This study determined the in vitro functional profile of 1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2… Expand
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2004
2004
OPC-14523 (OPC; [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate)] is a… Expand
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2004
2004
OPC-14523 (OPC; [1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate)] is a… Expand
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2002
2002
Sigma and 5-HT(1A) receptor stimulation can increase acetylcholine (ACh) release in the brain. Because ACh release facilitates… Expand
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2002
2002
Sigma and 5-HT1A receptor stimulation can increase acetylcholine (ACh) release in the brain. Because ACh release facilitates… Expand
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2001
2001
The antidepressant-like activity of a novel compound, OPC-14523, was investigated in comparison with the conventional… Expand
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