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ONO-2952

National Institutes of Health

Papers overview

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2020
2020
In preclinical models, it has been reported that social defeat stress activates microglial cells in the CNS. Translocator protein… Expand
2018
2018
Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder characterized by abdominal pain and abnormal bowel… Expand
2017
2017
ONO‐2952 is a novel and selective inhibitor of translocator protein 18 kDa that reduces stress‐induced defecation and visceral… Expand
2017
2017
ONO‐2952, a novel antagonist of translocator protein 18 kDa (TSPO), binds with high affinity to TSPO in rat brain and human tumor… Expand
2017
2017
We have previously shown that ONO-2952, a novel 18-kDa translocator protein (TSPO) antagonist, inhibits stress-induced… Expand
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2017
2017
  • J. Nee, A. Lembo
  • Alimentary pharmacology & therapeutics
  • 2017
  • Corpus ID: 28832373
There remains a significant unmet clinical need for safe and effective treatments in irritable bowel syndrome (IBS), particularly… Expand
2017
2017
on stress-induced rectal hyperalgesia and defecation in rats. Gastroenterology 2012; 142: S813–4. 3. Mitsui K. Anti stress… Expand
2016
2016
Abbreviations This article has not been copyedited and formatted. The final version may differ from this version. Abstract We… Expand
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2015
2015
Accumulating evidence has shown the pathophysiological significance of the translocator protein 18 kDa (TSPO) in the central… Expand
2015
2015
PURPOSE To investigate safety, tolerability, and pharmacokinetic properties of single and multiple doses of novel translocator… Expand
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