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OKY 1581

Known as: OKY-1581 
National Institutes of Health

Papers overview

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2001
2001
In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
1989
1989
The relation between thromboxane and prostaglandin synthesis in human decidua tissue: a comparison of eicosanoid synthesis in minced tissue with that in a cell-free preparation.
1986
1986
Improvement in Organ Blood Flow by Inhibition of Thromboxane Synthetase During Experimental Endotoxic Shock in the Rat
Summary: Endotoxic shock is associated with increased metabolism of arachidonic acid to thromboxane (Tx) and prostaglandins. This… 
1985
1985
Augmented thromboxane A2 generation and efficacy of its blockade in acute myocardial infarction.
1985
1985
Dietary protein intake conditions the degree of renal vasoconstriction in acute renal failure caused by ureteral obstruction.
Whole kidney inulin (CIn) and PAH (CPAH) clearances were measured after unilateral release of bilateral ureteral obstruction (BUO… 
1984
1984
Intravenous infusion of a selective inhibitor of thromboxane A2 synthetase in man: influence on thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and platelet aggregation.
The effect of the selective thromboxane A2 synthetase inhibitor OKY-1581, a pyridine derivative [sodium (E)-3-(4-(3-pyridylmethyl… 
Highly Cited
1983
Highly Cited
1983
Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets.
Highly Cited
1983
Highly Cited
1983
Potent vasoconstriction of the isolated perfused rat kidney by leukotrienes C4 and D4.
Chemically synthesized leukotriene C4, D4, and E4 have been compared for their effects on the isolated Krebs-perfused rat kidney… 
1981
1981
OKY-1581: a selective inhibitor of thromboxane synthesis in vivo and in vitro.
1981
1981
OKY-1581, a potential selective thromboxane synthetase inhibitor.
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