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OAS1 gene

Known as: OIAS, 2'-5'-oligoadenylate synthetase 1, OIASI 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Cytosolic DNA arising from intracellular bacterial or viral infections is a powerful pathogen-associated molecular pattern (PAMP… Expand
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Highly Cited
2011
Highly Cited
2011
The nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate innate immunity. Although the positive… Expand
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Highly Cited
2010
Highly Cited
2010
West Nile virus, first identified within the United States in 1999, has since spread across the continental states and infected… Expand
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Highly Cited
2010
Highly Cited
2010
BackgroundChanges in promoter DNA methylation pattern of genes involved in key biological pathways have been reported in… Expand
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Highly Cited
2009
Highly Cited
2009
West Nile virus (WNV) is a re-emerging pathogen that can cause fatal encephalitis. In mice, susceptibility to WNV has been… Expand
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Highly Cited
2008
Highly Cited
2008
BackgroundThe number of genome-wide association studies (GWAS) is growing rapidly leading to the discovery and replication of… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To study 5 type I interferon (IFN)-inducible genes (LY6E, OAS1, OASL, MX1, and ISG15) in patients with systemic lupus… Expand
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Highly Cited
2006
Highly Cited
2006
Multiple 2′-5′ oligoadenylate (2-5A) synthetases are important components of innate immunity in mammals. Gene families encoding… Expand
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Highly Cited
2005
Highly Cited
2005
Both genetic and nongenetic factors contribute to the development of type 1 diabetes. Many investigations, including prospective… Expand
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Highly Cited
2004
Highly Cited
2004
RNA interference is widely used to silence gene expression in mammalian cells. We recently reported that an shRNA expressed from… Expand
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