Nuclear Receptor ROR-Gamma

Known as: Retinoid-Related Orphan Receptor-Gamma, RORC, Nuclear Receptor RZR-Gamma 
Nuclear receptor ROR-gamma (518 aa, ~58 kDa) is encoded by the human RORC gene. This protein plays a role in ligand-mediated transcriptional… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
0102019972017

Papers overview

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Highly Cited
2011
Highly Cited
2011
The tumor microenvironment includes a complex network of immune T-cell subpopulations. In this study, we systematically analyzed… (More)
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Highly Cited
2011
Highly Cited
2011
Naturally occurring CD4(+)CD25(+)FOXP3(+) regulatory T cells suppress the activity of pathogenic T cells and prevent development… (More)
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Highly Cited
2010
Highly Cited
2010
The proinflammatory cytokine IL-17A is considered a crucial player in rheumatoid arthritis (RA) pathogenesis. In experimental… (More)
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Highly Cited
2010
Highly Cited
2010
We have previously shown that human Th17 lymphocytes are characterized by the selective expression of IL-23 receptor (IL-23R… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE To delineate the role of Th17 cells in the pathogenesis of autoimmune arthritides. METHODS Th17 cells were analyzed… (More)
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2010
2010
T helper 17 (Th17) cells and regulatory T (Treg) cells are two distinct subsets of CD4(+) T cells which have opposite effects on… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS Mucosal natural killer (NK) cells that produce interleukin (IL)-22 mediate intestinal homeostasis and… (More)
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Highly Cited
2009
Highly Cited
2009
Interleukin 22 (IL-22) is a member of the IL-10 cytokine family that is involved in inflammatory and wound healing processes… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND A novel T helper (Th) cell lineage, Th17, that exclusively produces the proinflammatory cytokine interleukin 17 (IL17… (More)
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1997
1997
The nuclear orphan receptor subfamily ROR/RZR is part of the steroid and thyroid hormone/retinoid receptor superfamily and… (More)
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