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Nuclear Receptor ROR-Gamma

Known as: Retinoid-Related Orphan Receptor-Gamma, RORC, Nuclear Receptor RZR-Gamma 
Nuclear receptor ROR-gamma (518 aa, ~58 kDa) is encoded by the human RORC gene. This protein plays a role in ligand-mediated transcriptional… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Specialized proresolving lipid mediators reduce human T cell activation and prevent TH1 and TH17 cell differentiation from naïve… Expand
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Highly Cited
2013
Highly Cited
2013
Aryl hydrocarbon receptor (Ahr) is crucial for the maintenance and function of group 3 innate lymphoid cells (ILCs), which are… Expand
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Highly Cited
2012
Highly Cited
2012
Myeloid-derived suppressor cells (MDSCs) have been a focus of recent study on tumor-mediated immune suppression. However, its… Expand
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Highly Cited
2011
Highly Cited
2011
Follicular T helper (Tfh) cells provide critical help to B cells for germinal center (GC) formation. Mutations affecting SLAM… Expand
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Highly Cited
2011
Highly Cited
2011
ABSTRACT We have previously reported that compromised interleukin 17A (IL-17A) production in the lungs increased susceptibility… Expand
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Highly Cited
2010
Highly Cited
2010
CD4+ T-helper cells that selectively produce interleukin (IL)-17 (TH17), are critical for host defence and autoimmunity. Although… Expand
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Highly Cited
2009
Highly Cited
2009
IL-27 is secreted by APCs in response to inflammatory stimuli and exerts a proinflammatory Th1-enhancing activity but also has… Expand
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Highly Cited
2009
Highly Cited
2009
Growth factor independent 1 (Gfi-1), a transcriptional repressor, is transiently induced during T cell activation. Interleukin… Expand
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Highly Cited
2008
Highly Cited
2008
T helper cells that produce IL-17 (TH17 cells) promote autoimmunity in mice and have been implicated in the pathogenesis of human… Expand
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Highly Cited
2007
Highly Cited
2007
After activation, CD4+ helper T (TH) cells differentiate into distinct effector subsets that are characterized by their unique… Expand
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