Nonoxynol

Known as: Nonoxynol [Chemical/Ingredient], Nonoxynols, Nonoxinol 
Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting… (More)
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (5)

Advantage-SC-film LucchiniEmulgen 911Nonoxynol-9
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PregnancySurfactant Activity [MoA]aspects of radiation effectschemical synthesis
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Broader (3)

Spermatocidal AgentsSurface-Active AgentsVaginal Creams, Foams, and Jellies

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories.
The first product to be clinically evaluated as a microbicide contained the nonionic surfactant nonoxynol-9… (More)
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Review
2005
Review
2005
In vitro and in vivo: the story of nonoxynol 9.
There is an urgent need to expand the range of interventions to prevent HIV transmission and acquisition, especially those that… (More)
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2002
2002
Comparative in vitro sensitivities of human immune cell lines, vaginal and cervical epithelial cell lines, and primary cells to candidate microbicides nonoxynol 9, C31G, and sodium dodecyl sulfate.
In experiments to assess the in vitro impact of the candidate microbicides nonoxynol 9 (N-9), C31G, and sodium dodecyl sulfate… (More)
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1999
1999
Effects of multiple applications of benzalkonium chloride and nonoxynol 9 on the vaginal epithelium in the pigtailed macaque (Macaca nemestrina).
OBJECTIVE Safe and effective vaginally applied microbicides could help to control the continuing spread of sexually transmitted… (More)
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Highly Cited
1998
Highly Cited
1998
A Controlled Trial of Nonoxynol 9 Film to Reduce Male-to-Female Transmission of Sexually Transmitted Diseases
 
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1994
1994
Contact photosensitivity to nonoxynol used in antiseptic preparations.
Nonoxynols are nonionic surface-active agents used as surfactant in numerous cosmetic products and antiseptic preparations… (More)
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Highly Cited
1992
Highly Cited
1992
Efficacy of nonoxynol 9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes.
OBJECTIVE To determine the efficacy of the nonoxynol 9 contraceptive sponge in preventing sexual acquisition of the human… (More)
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1989
1989
In vitro evaluations of condoms with and without nonoxynol 9 as physical and chemical barriers against Chlamydia trachomatis, herpes simplex virus type 2, and human immunodeficiency virus.
Simulated in vitro intercourse conditions demonstrated that unlubricated latex condoms provide an effective physical barrier to… (More)
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1988
1988
Condoms as physical and chemical barriers against human immunodeficiency virus.
In an in vitro model, 20 condoms containing 0.9 mL of 6.6% (vol/vol) nonoxynol 9 and ten condoms without nonoxynol 9 were tested… (More)
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1987
1987
In vitro activity of nonoxynol-9 on McCoy cells infected with Chlamydia trachomatis.
Nonoxynol-9, a nonionic detergent and active ingredient in spermicidal contraceptives, has been reported to have anti-chlamydial… (More)
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