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Nitrosamine Metabolism

Nitrosamine Metabolism involves important cellular biochemical detoxification reactions that chemically modify the N-nitroso derivatives of secondary… Expand
National Institutes of Health

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2012
2012
OBJECTIVES Alaska Native (AN) people have a high prevalence of tobacco use and associated morbidity and mortality when compared… Expand
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2006
2006
Polymorphisms in nitrosamine metabolism, DNA repair, and immune response genes have been associated with nasopharyngeal carcinoma… Expand
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2002
2002
Oesophageal cancer is one of the most common and lethal malignancies in the world. Despite many efforts, treatment is still… Expand
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1998
1998
Esophageal cancer has been associated with tobacco smoking, and nitrosamines are possible causative agents for this cancer. The… Expand
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Highly Cited
1993
Highly Cited
1993
We undertook this study to answer several questions regarding nitrosamine metabolism. Kinetics of nitrosamine metabolism showed… Expand
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Highly Cited
1992
Highly Cited
1992
Phenethyl isothiocyanate (PEITC), a constituent of cruciferous vegetables, has been shown to inhibit chemical carcinogenesis… Expand
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Highly Cited
1988
Highly Cited
1988
It has been reported that p.o. administration of diallyl sulfide (DAS), a naturally occurring component of garlic (Allium sativum… Expand
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1985
1985
Metabolism of nitrosamines was studied in a reconstituted monooxygenase system composed of cytochrome P-450 isozymes purified… Expand
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Highly Cited
1983
Highly Cited
1983
In order to elucidate the enzymic basis of nitrosamine metabolism, the in vitro metabolism of nitrosamines by rat liver… Expand
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1975
1975
A major proportion of bacterial types, common in the gastrointestinal tract of many animals and man, were active in degrading… Expand
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