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Niridazole

Known as: 2-Imidazolidinone, 1-(5-nitro-2-thiazolyl)-, Niridazole [Chemical/Ingredient] 
An antischistosomal agent that has become obsolete.
National Institutes of Health

Related topics

Related topics

18 relations

Narrower (8)

4'-methylniridazole4,5-dehydroniridazole4-hydroxyniridazole4-ketoniridazole

Broader (2)

AmebicidesSchistosomicides
In BloodPoisoning by anthelminthicsagonistsanalogs & derivatives

Papers overview

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Highly Cited
1989
Highly Cited
1989
The popliteal lymph node assay in mice to screen for the immune disregulating potential of chemicals--a preliminary study.
Highly Cited
1986
Highly Cited
1986
Schistosoma mansoni: chemotherapy of infections of different ages.
Highly Cited
1985
Highly Cited
1985
Schistosoma mansoni: reduced efficacy of chemotherapy in infected T-cell-deprived mice.
Highly Cited
1984
Highly Cited
1984
Strongyloides stercoralis: hyperinfection in immunosuppressed dogs.
Highly Cited
1982
Highly Cited
1982
Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents.
Highly Cited
1981
Highly Cited
1981
Evidence for the existence of a family of bacterial nitroreductases capable of activating nitrated polycyclics to mutagens.
A derivative of Salmonella typhimurium TA98 which does not respond to the potent mutagenicity of 1,8-dinitropyrene is described… 
Highly Cited
1980
Highly Cited
1980
Relative importance of bacterial and mammalian nitroreductases for niridazole mutagenesis.
Niridazole is a nitrothiazole anthelmintic agent used to treat schistosomiasis. Its antibacterial activity was found to require… 
Highly Cited
1975
Highly Cited
1975
Detection of mutagenic activity of metronidazole and niridazole in body fluids of humans and mice.
After humans were treated at therapeutic doses with the trichomonacide metronidazole (Flagyl) and the antischistosomal agent… 
Highly Cited
1975
Highly Cited
1975
Niridazole. II. A potent long-acting suppressant of cellular hypersensitivity.
Niridazole, a human anthelminthic drug, is shown to be a potent long-acting suppressor of delayed hypersensitivity. Much lower… 
Highly Cited
1974
Highly Cited
1974
Anti-inflammatory effects of tartar emetic and niridazole: suppression of schistosome egg granuloma.
Treatment of cerebral schistosomiasis japonica with tartar emetic produces a remarkable and rapid improvement which cannot be… 
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