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Niridazole

Known as: 2-Imidazolidinone, 1-(5-nitro-2-thiazolyl)-, Niridazole [Chemical/Ingredient] 
An antischistosomal agent that has become obsolete.
National Institutes of Health

Papers overview

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Highly Cited
1986
Highly Cited
1986
Mice were treated with potassium antimony tartrate, hycanthone, oxamniquine, niridazole, or praziquantel at different times after… Expand
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Highly Cited
1981
Highly Cited
1981
A derivative of Salmonella typhimurium TA98 which does not respond to the potent mutagenicity of 1,8-dinitropyrene is described… Expand
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Highly Cited
1980
Highly Cited
1980
Niridazole is a nitrothiazole anthelmintic agent used to treat schistosomiasis. Its antibacterial activity was found to require… Expand
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Highly Cited
1975
Highly Cited
1975
After humans were treated at therapeutic doses with the trichomonacide metronidazole (Flagyl) and the antischistosomal agent… Expand
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Highly Cited
1975
Highly Cited
1975
The mutagenic activity of nitrofuran derivatives and of niridazole is easily demonstrated by spot tests using E. coli WP2 and its… Expand
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Highly Cited
1975
Highly Cited
1975
Niridazole, a human anthelminthic drug, is shown to be a potent long-acting suppressor of delayed hypersensitivity. Much lower… Expand
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1975
1975
Niridazole, an anti-parasitic drug, suppresses manifestations of delayed hypersensitivity and retards allograft rejection in… Expand
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Highly Cited
1974
Highly Cited
1974
Treatment of cerebral schistosomiasis japonica with tartar emetic produces a remarkable and rapid improvement which cannot be… Expand
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Highly Cited
1971
Highly Cited
1971
Abstract The soluble fraction of liver contains an enzyme that catalyzes the reduction of niridazole by either NADH or… Expand
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Highly Cited
1971
Highly Cited
1971
Abstract Investigations were carried out with liver microsomes to identify the metabolites and to characterize the enzyme… Expand
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