Nicotinamide Phosphoribosyltransferase

Known as: NAMPT Protein, Phosphoribosyltransferase, Nicotinamide, Colony-Enhancing Factor, Pre-B-Cell 
An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting… (More)
National Institutes of Health

Related topics

Related topics

13 relations
In BloodNAMPT genePBEF1 wt AlleleProcess of secretion
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Narrower (3)

nicotinamide phosphoribosyltransferase, humannicotinamide phosphoribosyltransferase, mousenicotinamide phosphoribosyltransferase, rat

Broader (1)

pentosyltransferase

Papers overview

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2011
2011
Nicotinamide Phosphoribosyltransferase/Visfatin Does Not Catalyze Nicotinamide Mononucleotide Formation in Blood Plasma
Nicotinamide (Nam) phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in mammalian NAD synthesis, catalyzing… (More)
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Highly Cited
2009
Highly Cited
2009
Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide.
AIMS Perivascular adipose tissue (PVAT) inhibits vascular smooth muscle cell (VSMC) contraction and stimulates VSMC proliferation… (More)
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Highly Cited
2009
Highly Cited
2009
Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity
Extracellular pre-B cell colony-enhancing factor/nicotinamide phosphoribosyltransferase/visfatin (ePBEF/NAMPT/visfatin) is an… (More)
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Highly Cited
2008
Highly Cited
2008
Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase/Visfatin Enzymatic Activity Identifies a New Inflammatory Pathway Linked to NAD
Nicotinamide phosphoribosyltransferase (NAMPT), also known as visfatin, is the rate-limiting enzyme in the salvage pathway of NAD… (More)
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Highly Cited
2008
Highly Cited
2008
Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kappaB activation in endothelial cells.
Visfatin has recently been identified as a novel visceral adipokine which may be involved in obesity-related vascular disorders… (More)
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2008
2008
Serum visfatin concentrations in obese adolescents and its correlation with age and high-density lipoprotein cholesterol.
Visfatin was recently identified as an adipocytokine and has insulin mimetic properties, but its role in adolescents remains… (More)
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Highly Cited
2007
Highly Cited
2007
Plasma visfatin levels in patients with newly diagnosed and untreated type 2 diabetes mellitus and impaired glucose tolerance.
Visfatin, a new adipokine, facilitates adipogenesis and has insulin-mimetic properties. We aimed to investigate the plasma… (More)
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Highly Cited
2007
Highly Cited
2007
Circulating levels of visfatin/pre-B-cell colony-enhancing factor 1 in relation to genotype, GFR, body composition, and survival in patients with CKD.
BACKGROUND Visfatin, also known as pre-B-cell colony-enhancing factor 1 (PBEF-1), recently was shown to be secreted from… (More)
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Highly Cited
2007
Highly Cited
2007
Association between plasma visfatin and vascular endothelial function in patients with type 2 diabetes mellitus.
Visfatin is a newly identified adipocytokine that mimics insulin action. However, the pathophysiological role of visfatin in… (More)
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Highly Cited
2002
Highly Cited
2002
Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis.
The murine homologue of the previously identified human "pre-B-cell colony-enhancing factor" (PBEF) gene coding for a putative… (More)
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