nicotinamide phosphoribosyltransferase, human

Known as: PBEF, human, Pre-B Cell-Enhancing Factor, pre-B-cell colony-enhancing factor, human 
Nicotinamide phosphoribosyltransferase (491 aa, ~56 kDa) is encoded by the human NAMPT gene. This protein plays a role in both NAD biosynthesis and… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Recent studies have shown that overweight and obesity play an important role in the development of osteoarthritis (OA). However… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Type 2 diabetes (T2D) has become epidemic in our modern lifestyle, likely due to calorie-rich diets overwhelming our adaptive… (More)
Is this relevant?
Highly Cited
2011
Highly Cited
2011
OBJECTIVE Stroke is a leading cause of mortality and disability. Nicotinamide phosphoribosyltransferase (Nampt) is the rate… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Nicotinamide phosphoribosyltransferase (NAMPT) is a multifunctional protein potentially involved in obesity and glucose… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
RATIONALE NAD+ acts not only as a cofactor for cellular respiration but also as a substrate for NAD(+)-dependent enzymes, such as… (More)
  • figure 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Extracellular pre-B cell colony-enhancing factor/nicotinamide phosphoribosyltransferase/visfatin (ePBEF/NAMPT/visfatin) is an… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Many metabolic and physiological processes display circadian oscillations. We have shown that the core circadian regulator, CLOCK… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 1
Is this relevant?
Highly Cited
2009
Highly Cited
2009
AIMS Perivascular adipose tissue (PVAT) inhibits vascular smooth muscle cell (VSMC) contraction and stimulates VSMC proliferation… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Intracellular nicotinamide phosphoribosyltransferase (iNampt) is an essential enzyme in the NAD biosynthetic pathway. An… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Recent studies have revealed new roles for NAD and its derivatives in transcriptional regulation. The evolutionarily conserved… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?