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Neutron Capture Therapy

Known as: Neutron Capturing Therapy, Therapy, Neutron Capture, Therapy, Neutron Capturing 
A technique for the treatment of neoplasms in which an isotope is introduced into target cells followed by irradiation with thermal neutrons.
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Radionuclide therapy
neutron radiationnursing therapystandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Boron in drug discovery: carboranes as unique pharmacophores in biologically active compounds.
Boron in Drug Discovery: Carboranes as Unique Pharmacophores in Biologically Active Compounds Fatiah Issa, Michael Kassiou, and… Expand
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Highly Cited
2009
Highly Cited
2009
Boron neutron capture therapy for newly diagnosed glioblastoma.
PURPOSE The efficacy, safety, and dose distribution of neutron capture therapy (NCT) were evaluated in 15 patients with newly… Expand
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Highly Cited
2007
Highly Cited
2007
A critical examination of the results from the Harvard-MIT NCT program phase I clinical trial of neutron capture therapy for intracranial disease
SummaryA phase I trial was designed to evaluate normal tissue tolerance to neutron capture therapy (NCT); tumor response was also… Expand
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Highly Cited
2004
Highly Cited
2004
Comparison of cell uptake, biodistribution and tumor retention of folate-coated and PEG-coated gadolinium nanoparticles in tumor-bearing mice.
The purpose of these studies was to compare the cell uptake, biodistribution and tumor retention of folate-coated and PEG-coated… Expand
Highly Cited
2002
Highly Cited
2002
Reference dosimetry calculations for neutron capture therapy with comparison of analytical and voxel models.
As clinical trials of Neutron Capture Therapy (NCT) are initiated in the U.S. and other countries, new treatment planning codes… Expand
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Highly Cited
1994
Highly Cited
1994
Boron neutron capture therapy of malignant melanoma using 10B-paraboronophenylalanine with special reference to evaluation of radiation dose and damage to the normal skin.
A treatment regimen for boron neutron capture therapy of malignant melanomas is described using 10B-paraboronophenylalanine as… Expand
Highly Cited
1992
Highly Cited
1992
Progress in Neutron Capture Therapy for Cancer
Prognosis for some cancers is good, but for others, few patients will survive 12 months. This latter group of cancers is… Expand
Review
1989
Review
1989
New thermal neutron capture therapy for malignant melanoma: melanogenesis-seeking 10B molecule-melanoma cell interaction from in vitro to first clinical trial.
Human melanoma regression by single thermal neutron capture therapy (NCT) using melanoma-seeking 10B compounds has been achieved… Expand
Highly Cited
1985
Highly Cited
1985
Current status of 10B-neutron capture therapy: enhancement of tumor dose via beam filtration and dose rate, and the effects of these parameters on minimum boron content: a theoretical evaluation.
At least 8 classes of compounds are being evaluated in various laboratories around the world as possible vehicles for the… Expand
Highly Cited
1982
Highly Cited
1982
Specific killing effect of 10B1-para-boronophenylalanine in thermal neutron capture therapy of malignant melanoma: in vitro radiobiological evaluation.
A 10B-dopa analogue, 10B1-para-boronophenylalanine (10B1-BPA) has been found to have a marked melanoma killing effect as… Expand
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