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Neutron Capture Therapy

Known as: Neutron Capturing Therapy, Therapy, Neutron Capture, Therapy, Neutron Capturing 
A technique for the treatment of neoplasms in which an isotope is introduced into target cells followed by irradiation with thermal neutrons.
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Radionuclide therapy
neutron radiationnursing therapystandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Block copolymer‐boron cluster conjugate for effective boron neutron capture therapy of solid tumors
&NA; Boron neutron capture therapy is a promising tumor treatment method, though its wide application has been limited due to the… Expand
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Review
2011
Review
2011
Boron in drug discovery: carboranes as unique pharmacophores in biologically active compounds.
Boron in Drug Discovery: Carboranes as Unique Pharmacophores in Biologically Active Compounds Fatiah Issa, Michael Kassiou, and… Expand
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Highly Cited
2009
Highly Cited
2009
Boron neutron capture therapy for newly diagnosed glioblastoma.
PURPOSE The efficacy, safety, and dose distribution of neutron capture therapy (NCT) were evaluated in 15 patients with newly… Expand
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Review
2007
Review
2007
Carboranyl thymidine analogues for neutron capture therapy.
Neutron capture therapy (NCT) is a binary radio-chemotherapeutic modality for the treatment of cancer. A major focus of NCT… Expand
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Highly Cited
2007
Highly Cited
2007
A critical examination of the results from the Harvard-MIT NCT program phase I clinical trial of neutron capture therapy for intracranial disease
SummaryA phase I trial was designed to evaluate normal tissue tolerance to neutron capture therapy (NCT); tumor response was also… Expand
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Highly Cited
2004
Highly Cited
2004
Comparison of cell uptake, biodistribution and tumor retention of folate-coated and PEG-coated gadolinium nanoparticles in tumor-bearing mice.
The purpose of these studies was to compare the cell uptake, biodistribution and tumor retention of folate-coated and PEG-coated… Expand
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Highly Cited
2002
Highly Cited
2002
Reference dosimetry calculations for neutron capture therapy with comparison of analytical and voxel models.
As clinical trials of Neutron Capture Therapy (NCT) are initiated in the U.S. and other countries, new treatment planning codes… Expand
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2002
2002
Treatment planning and dosimetry for the Harvard-MIT Phase I clinical trial of cranial neutron capture therapy.
PURPOSE A Phase I trial of cranial neutron capture therapy (NCT) was conducted at Harvard-MIT. The trial was designed to… Expand
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1994
1994
Boron neutron capture therapy of malignant melanoma using 10B-paraboronophenylalanine with special reference to evaluation of radiation dose and damage to the normal skin.
A treatment regimen for boron neutron capture therapy of malignant melanomas is described using 10B-paraboronophenylalanine as… Expand
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Highly Cited
1985
Highly Cited
1985
Current status of 10B-neutron capture therapy: enhancement of tumor dose via beam filtration and dose rate, and the effects of these parameters on minimum boron content: a theoretical evaluation.
At least 8 classes of compounds are being evaluated in various laboratories around the world as possible vehicles for the… Expand
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