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Neuropilin-1

Known as: Npn 1 Protein, A5 Antigen, NRP1 Protein 
A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa… 
National Institutes of Health

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In BloodNRP1 geneNRP1 wt Alleleagonists

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Neuropilin-1, Human

Papers overview

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Highly Cited
2007
Highly Cited
2007
Targeting Neuropilin 1 as an Antitumor Strategy in Lung Cancer
Purpose: Neuropilin 1 (NRP1) is a mediator of lung branching and angiogenesis in embryonic development and angiogenesis in cancer… 
Highly Cited
2002
Highly Cited
2002
Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis
Neuropilins (NP1 and NP2) are vascular endothelial growth factor (VEGF) receptors that mediate developmental and tumor… 
Highly Cited
2002
Highly Cited
2002
Characterization of Neuropilin-1 Structural Features That Confer Binding to Semaphorin 3A and Vascular Endothelial Growth Factor 165*
Neuropilin-1 (Npn-1) is a receptor for both semaphorin 3A (Sema3A) and vascular endothelial growth factor 165 (VEGF165). To… 
Review
2002
Review
2002
The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis.
Highly Cited
2000
Highly Cited
2000
Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity.
Neuropilin-1 (NRP1) is a 130-kDa transmembrane receptor for semaphorins, mediators of neuronal guidance, and for vascular… 
Highly Cited
2000
Highly Cited
2000
The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1.
Neuropilin-1 (NP-1) was first identified as a semaphorin receptor involved in neuron guidance. Subsequent studies demonstrated… 
Highly Cited
2000
Highly Cited
2000
Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia.
Vascular endothelial growth factor (VEGF) is a hypoxia-inducible angiogenic peptide with recently identified neurotrophic effects… 
Highly Cited
1999
Highly Cited
1999
A requirement for neuropilin-1 in embryonic vessel formation.
Neuropilin-1 is a membrane protein that is expressed in developing neurons and functions as a receptor or a component of the… 
Highly Cited
1999
Highly Cited
1999
Plexin-Neuropilin-1 Complexes Form Functional Semaphorin-3A Receptors
Highly Cited
1998
Highly Cited
1998
Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors
Neuropilin-1 (NP-1) has been identified as a necessary component of a semaphorin D (SemD) receptor that repulses dorsal root… 
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