Neuropilin-1, Human

Known as: VEGF165R, Blood Dendritic Cell Antigen 4, Neuropilin-1 
Neuropilin-1 (923 aa, ~103 kDa) is encoded by the human NRP1 gene. This protein is involved in growth factor-mediated signaling.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Foxp3(+) CD4(+) T helper cells called regulatory T (T reg) cells play a key role in controlling reactivity to self-antigens and… (More)
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Highly Cited
2012
Highly Cited
2012
Foxp3 activity is essential for the normal function of the immune system. Two types of regulatory T (T reg) cells express Foxp3… (More)
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Highly Cited
2007
Highly Cited
2007
Neuropilin-1 (NRP1) guides the development of the nervous and vascular systems. Binding to either semaphorins or VEGF, NRP1 acts… (More)
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Highly Cited
2002
Highly Cited
2002
Mutations in the L1 gene induce a spectrum of human neurological disorders due to abnormal development of several brain… (More)
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Highly Cited
2000
Highly Cited
2000
Neuropilin-1 (NP-1) was first identified as a semaphorin receptor involved in neuron guidance. Subsequent studies demonstrated… (More)
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Highly Cited
1999
Highly Cited
1999
Neuropilin-1 is a membrane protein that is expressed in developing neurons and functions as a receptor or a component of the… (More)
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Highly Cited
1999
Highly Cited
1999
Class 1 and 3 semaphorins repulse axons but bind to different cell surface proteins. We find that the two known semaphorin… (More)
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Highly Cited
1999
Highly Cited
1999
Neuropilin-1 (NRP1) is a receptor for two unrelated ligands with disparate activities, vascular endothelial growth factor-165… (More)
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Highly Cited
1998
Highly Cited
1998
Vascular endothelial growth factor (VEGF), a major regulator of angiogenesis, binds to two receptor tyrosine kinases, KDR/Flk-1… (More)
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Highly Cited
1998
Highly Cited
1998
Placenta growth factor (PlGF) belongs to the family of vascular endothelial growth factors (VEGFs). It binds to the flt-1 VEGF… (More)
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