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Abnormal protein aggregation is emerging as a common theme in the pathogenesis of neurodegenerative disease. Our previous studies… Expand We demonstrate that the degree of neuronal development of PC-12 cell differentiation can be quantified by the expression of… Expand OBJECTIVE
NMDA receptor dysfunction has been implicated in the pathophysiology of schizophrenia. The NMDA receptor is a… Expand Abstract : Neurofilament‐L (NF‐L), one subunit of the neuronal intermediate filaments, is a major element of neuronal… Expand Abstract: Ser55 of neurofilament L (NF‐L) is reported to be partly phosphorylated in neurons and to be phosphorylated by cyclic… Expand Abstract: Superoxide dismutase (SOD) catalyzes the nitration of specific tyrosine residues in proteins by peroxynitrite (ONOO… Expand We report here the developmental activity of regulatory elements that reside within 1.7 kilobases of the murine neurofilament… Expand Neurofilaments (NFs), composed of three distinct subunits NF-L, NF-M, and NF-H, are neuron-specific intermediate filaments… Expand The existence of a neurofilament-deficient mutant of Japanese quail was recently documented (Yamasaki, H., C. Itakura, and M… Expand We have generated transgenic mice containing additional copies of the murine NF-L gene in order to examine the consequences of… Expand