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Neurexin-3

Known as: Neurexin III, Neurexin III-Alpha, Neurexin-3-Alpha 
Neurexin-3 (1643 aa, ~181 kDa) is encoded by the human NRXN3 gene. This protein is involved in cell recognition and cell adhesion.
National Institutes of Health

Related topics

Related topics

11 relations
Cell AdhesionCell-Cell Adhesion ProcessClusters of differentiationEGF-Like Domain
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses
AMPA- and NMDA-type glutamate receptors mediate distinct postsynaptic signals that differ characteristically among synapses. How… Expand
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2019
2019
Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters
Using super-resolution microscopy, Trotter et al. illuminate an unexpected nanoscale organization of excitatory synapses in which… Expand
2018
2018
A Parallel Reaction Monitoring Mass Spectrometric Method for Analysis of Potential CSF Biomarkers for Alzheimer's Disease
The aim of this study was to develop and evaluate a parallel reaction monitoring mass spectrometry (PRM‐MS) assay consisting of a… Expand
Highly Cited
2015
Highly Cited
2015
Distinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses
α- and β-neurexins are presynaptic cell-adhesion molecules whose general importance for synaptic transmission is well documented… Expand
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Highly Cited
2013
Highly Cited
2013
Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking
Neurexins are essential presynaptic cell adhesion molecules that are linked to schizophrenia and autism and are subject to… Expand
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2011
2011
Associations among types of impulsivity, substance use problems and neurexin-3 polymorphisms.
BACKGROUND Some of the genetic vulnerability for addiction may be mediated by impulsivity. This study investigated relationships… Expand
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2011
2011
CLC-3 spices up GABAergic synaptic vesicles
How does chloride enter synaptic vesicle, and is it required for neurotransmitter uptake? A new study finds that the chloride… Expand
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Highly Cited
2002
Highly Cited
2002
Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.
Neurexins are neuron-specific vertebrate proteins with hundreds of differentially spliced isoforms that may function in synapse… Expand
Highly Cited
2001
Highly Cited
2001
Most of the human genome is transcribed.
Initial sequence annotations of the human genome have uncovered at least 32,000 genes (International Human Genome Sequencing… Expand
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Highly Cited
1993
Highly Cited
1993
Neurexin III alpha: extensive alternative splicing generates membrane-bound and soluble forms.
The structure of neurexin III alpha was elucidated from overlapping cDNA clones. Neurexin III alpha is highly homologous to… Expand
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