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Nesbuvir

Known as: 5-Cyclopropyl-2-(4-fluorophenyl)-6-((2-hydroxyethyl)(methylsulfonyl)amino)-N-methyl-1-benzofuran-3-carboxamide 
A non-nuceoside polymerase inhibitor with activity against hepatitis C virus (HCV). Nesbuvir binds to the palm site II pocket of HCV NS5B polymerase… Expand
National Institutes of Health

Papers overview

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2018
2018
This letter describes the discovery of a fused benzofuran scaffold viable for preparing a series of novel potent HCV NS5B… Expand
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2018
2018
With the introduction of direct-acting antivirals (DAAs), treatment against hepatitis C virus (HCV) has significantly improved… Expand
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2017
2017
With the introduction of direct-acting antivirals (DAAs), treatment against hepatitis C virus (HCV) has significantly improved… Expand
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2017
2017
&NA; The development of direct‐acting antivirals (DAAs) has significantly improved hepatitis C virus (HCV) treatment. However… Expand
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2017
2017
Allosteric inhibitors of hepatitis C virus (HCV) non-structural protein 5B (NS5B) polymerase are effective for treatment of… Expand
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2015
2015
Hepatitis C virus, an enveloped positive – stranded RNA virus and the sole member of the genus Hepacivirus within the… Expand
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2014
2014
Direct-acting antivirals (DAAs) targeting proteins encoded by the hepatitis C virus (HCV) genome have great potential for the… Expand
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