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Neovastat
Known as:
Neovastat/AE-941
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
AE-941
Shark cartilage extract
GW786034
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Neovastat (Æ-941) inhibits the airway inflammation via VEGF and HIF-2α suppression
S. Lee
,
Su-Mi Chung
2007
Corpus ID: 72262995
Abstract Vascular endothelial growth factor (VEGF) contributes to airway inflammation and angiogenesis in asthma. Hypoxia…
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Highly Cited
2004
Highly Cited
2004
Antiangiogenic and antimetastatic properties of Neovastat (Æ-941), an orally active extract derived from cartilage tissue
E. Dupont
,
P. Falardeau
,
+4 authors
M. Alaoui-Jamali
Clinical & Experimental Metastasis
2004
Corpus ID: 27643318
A novel naturally occurring antiangiogenic agent isolated from cartilage, referred to as Neovastat (Æ-941), was examined for its…
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2004
2004
Activation of tissue plasminogen activator gene transcription by Neovastat, a multifunctional antiangiogenic agent.
D. Gingras
,
C. Nyalendo
,
Geneviève Di Tomasso
,
B. Annabi
,
R. Béliveau
Biochemical and biophysical research…
2004
Corpus ID: 33398082
We recently reported that Neovastat, an antiangiogenic drug that is currently undergoing Phase III clinical trials for the…
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Highly Cited
2003
Highly Cited
2003
Phase I/II trial of the safety and efficacy of AE-941 (Neovastat) in the treatment of non-small-cell lung cancer.
J. Latreille
,
G. Batist
,
+7 authors
E. Dupont
Clinical lung cancer
2003
Corpus ID: 23519964
AE-941 (Neovastat), an antiangiogenic component extracted from cartilage, selectively competes for the binding of vascular…
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Highly Cited
2002
Highly Cited
2002
Neovastat (AE-941) in refractory renal cell carcinoma patients: report of a phase II trial with two dose levels.
G. Batist
,
F. Patenaude
,
+5 authors
E. Dupont
Annals of oncology : official journal of the…
2002
Corpus ID: 4681226
BACKGROUND renal cell carcinoma (RCC) is a potential target for anti-angiogenic drugs because of its high vascularization…
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Highly Cited
2002
Highly Cited
2002
The antiangiogenic agent Neovastat (AE-941) induces endothelial cell apoptosis.
D. Boivin
,
Sébastien P. Gendron
,
E. Beaulieu
,
D. Gingras
,
R. Béliveau
Molecular cancer therapeutics
2002
Corpus ID: 35026918
Neovastat (AE-941), a naturally occurring multifunctional antiangiogenic agent, has been shown to inhibit key components of the…
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Highly Cited
2002
Highly Cited
2002
Neovastat (AE-941), an inhibitor of angiogenesis: Randomized phase I/II clinical trial results in patients with plaque psoriasis.
D. Sauder
,
J. Dekoven
,
P. Champagne
,
Daniel Croteau
,
E. Dupont
Journal of the American Academy of Dermatology
2002
Corpus ID: 27947709
There is considerable evidence to support an immunopathogenic basis of psoriasis. However, changes such as altered angiogenesis…
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Highly Cited
2002
Highly Cited
2002
The antiangiogenic agent neovastat (AE-941) inhibits vascular endothelial growth factor-mediated biological effects.
R. Béliveau
,
D. Gingras
,
+15 authors
E. Dupont
Clinical cancer research : an official journal of…
2002
Corpus ID: 21607296
PURPOSE Vascular endothelial growth factor (VEGF) is a potent regulator of angiogenesis, which exerts direct effects on vascular…
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Highly Cited
2002
Highly Cited
2002
The effect of Neovastat (AE-941) on an experimental metastatic bone tumor model.
M. H. Weber
,
J. Lee
,
F. Orr
International journal of oncology
2002
Corpus ID: 5859415
Bone metastases are generally associated with bone destruction which occurs in response to factors secreted by metastatic cells…
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Review
2001
Review
2001
Neovastat, a naturally occurring multifunctional antiangiogenic drug, in phase III clinical trials.
P. Falardeau
,
P. Champagne
,
P. Poyet
,
C. Hariton
,
E. Dupont
Seminars in oncology
2001
Corpus ID: 37951961
Recent studies have indicated that bone marrow angiogenesis is increased in multiple myeloma, suggesting that treatment with an…
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