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Negative Elongation Factor B, human

Known as: Negative Elongation Factor Polypeptide B, Negative Elongation Factor B, cofactor of BRCA1 protein, human 
Negative elongation factor B (580 aa, ~66 kDa) is encoded by the human NELFB gene. This protein is involved in the negative regulation of transcript… 
National Institutes of Health

Related topics

Related topics

9 relations
Cell NucleusGenes, RegulatorNELFB geneNELFB wt Allele

Broader (1)

negative elongation factor

Papers overview

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2018
2018
Negative elongation factor is essential for endometrial function
Pausing of RNA polymerase II (Pol II) during early transcription, mediated by the negative elongation factor (NELF) complex… 
Review
2015
Review
2015
Translational Initiation at a Non-AUG Start Codon for Human and Mouse Negative Elongation Factor-B
Negative elongation factor (NELF), a four-subunit protein complex in metazoan, plays an important role in regulating promoter… 
2015
2015
Structural and functional studies on the negative elongation factor
In many metazoans RNA polymerase II is stably paused after transcribing 20-60 nucleotides of a gene and awaits controlled release… 
2014
2014
Negative Elongation Factor Controls Energy Homeostasis in Cardiomyocytes
2011
2011
Genetic and Genomic Analyses of RNA Polymerase II-pausing Factor in Regulation of Mammalian Transcription and Cell Growth*
Background: RNA polymerase II pausing is an important regulatory step in eukaryotic transcription. Results: Genetic ablation of… 
Highly Cited
2009
Highly Cited
2009
Mouse Cofactor of BRCA1 (Cobra1) Is Required for Early Embryogenesis
Background Negative elongation factor (NELF) is a four-subunit protein complex conserved from Drosophila to humans. In vitro… 
2009
2009
Warten auf die Transkription: Die humanen Elongationsfaktoren NELF und DSIF
The E subunit of the human heterotetrameric negative transcription elongation factor (NELFE) contains a canonical R R RNA… 
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