Nafcillin

Known as: (2S,5R,6R)-6-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (2-Ethoxy-1-naphthyl)penicillin, Naphthamidopenicillin 
A semi-synthetic naphthalene and beta-lactam antibiotic with antibacterial activity. Nafcillin inhibits bacterial wall synthesis by a mechanism of… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
BACKGROUND The high prevalence of methicillin-resistant S. aureus (MRSA) has led clinicians to select antibiotics that have… (More)
  • table 1
  • table 2
Is this relevant?
2008
2008
The goal of this investigation is to develop poly(DL-lactide-co-glycolide) (PLGA) nanoparticles for the delivery of antibiotics… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Extracellular protein toxins contribute to the pathogenesis of a wide variety of Staphylococcus aureus infections. The present… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
We evaluated the impact of high (9.5 log10 CFU/g) and moderate (5.5 log10 CFU/g) inocula of methicillin-susceptible and… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Staphylococcus aureus bacteremia is associated with substantial morbidity. Recurrence is common, but incidence and risk factors… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
Is this relevant?
1986
1986
A controlled trial of treatment of chronic osteomyelitis caused by Staphylococcus aureus compared nafcillin alone with nafcillin… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
Fifty-three (3.6%; actuarially 4.1% at 48 months) of 1465 consecutive in-hospital survivors of valve replacement from 1975 to… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
1982
Highly Cited
1982
Single (nafcillin for 6 weeks) and combined (nafcillin for 6 weeks plus gentamicin for 2 weeks) drug regimens were compared in… (More)
Is this relevant?
Highly Cited
1981
Highly Cited
1981
We developed a candidate Reference Method for measuring total serum protein by use of the biuret reaction. The method involves a… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
1976
1976
The bactericidal rate of nafcillin and the combination of nafcillin and gentamicin against Staphylococcus aureus were compared in… (More)
Is this relevant?