Nacystelyn
National Institutes of Health
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Adenoviral vector-mediated gene delivery has been vastly investigated for cystic fibrosis (CF) gene therapy; however, one of its…
Increased levels of proinflammatory cytokines are present in bronchoalveolar lavage fluid in various lung diseases. Redox…
Background. Drugs blocking dendritic cell (DC) maturation might be useful in transplantation by inhibiting the induction of…
The aim of the present studies was to investigate the tolerability and activity of a novel mucolytic drug, Nacystelyn (NAL), for…
OBJECTIVE
To investigate the effect of dornase alfa (DA), Nacystelyn (NAL) and their combination on mucociliary transportability…
Trials of gene transfer for cystic fibrosis (CF) are currently underway. However, direct application to the airways may be…
In lung diseases such as chronic obstructive pulmonary disease (COPD) or cystic fibrosis, the activation of phagocytic cells…
The objective of this study was to evaluate the individual and combined effects of Nacystelyn (NAL) and rhDNase in vitro on the…
Thiol-containing molecules possess antioxidant properties that are of interest in the pharmacological inactivation of reactive…