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Nacystelyn

National Institutes of Health

Papers overview

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2012
2012
Vector Specific Tolerance Induction for Airwary Gene Therapy
The success of adenoviral mediated airway gene therapy is hindered by host immune responses against adenoviral vectors. Helper… 
2008
2008
N-Acetylcysteine Derivative Inhibits CD40-Dependent Proinflammatory Properties of Human Pancreatic Duct Cells
Objectives: We recently observed that duct cells constitutively express CD40, a membrane molecule whose engagement results in… 
2007
2007
Nacystelyn enhances adenoviral vector-mediated gene delivery to mouse airways
Adenoviral vector-mediated gene delivery has been vastly investigated for cystic fibrosis (CF) gene therapy; however, one of its… 
2003
2003
Dendritic cells exposed to nacystelyn are refractory to maturation and promote the emergence of alloreactive regulatory T cells
Background. Drugs blocking dendritic cell (DC) maturation might be useful in transplantation by inhibiting the induction of… 
2002
2002
Inhibitory effects of thiol-containing drugs on erythrocyte oxidative damages investigated with an improved assay system.
2002
2002
Additive effect of dornase alfa and Nacystelyn on transportability and viscoelasticity of cystic fibrosis sputum.
OBJECTIVE To investigate the effect of dornase alfa (DA), Nacystelyn (NAL) and their combination on mucociliary transportability… 
2001
2001
Deposition of Nacystelyn from a Dry Powder Inhaler in Healthy Volunteers and Cystic Fibrosis Patients
The aim of this study was to compare, using gamma scintigraphy, the lung deposition of a novel mucoactive agent, Nacystelyn (NAL… 
1996
1996
Reduction in viscoelasticity in cystic fibrosis sputum in vitro using combined treatment with Nacystelyn and rhDNase
The objective of this study was to evaluate the individual and combined effects of Nacystelyn (NAL) and rhDNase in vitro on the… 
1996
1996
NEUE PERSPEKTIVEN DER ANTIOXIDANTIENTHERAPIE MIT THIOLEN: NACYSTELYN
1995
1995
A comparison of a new mucolytic N-acetylcysteine L-lysinate with N-acetylcysteine: airway epithelial function and mucus changes in dog.
A newly synthesized mucolytic agent, N-acetylcysteine L-lysinate (Nacystelyn) was studied. Tracheal mucus velocity (TMV… 
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