NU 7026

Known as: NU-7026, NU7026 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2015
051020032015

Papers overview

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2011
2011
First line chemotherapeutics for brain tumors (malignant gliomas) are alkylating agents such as temozolomide and nimustine… (More)
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2011
2011
The use of lentiviral vectors extends from the laboratory, where they are used for basic studies in virology and as gene transfer… (More)
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2010
2010
Programmed cell death is a crucial process in neural development that affects mature neurons and glial cells, as well as… (More)
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2009
2009
When DNA double-strand breaks (DSB) are induced by ionizing radiation (IR) in cells, histone H2AX is quickly phosphorylated into… (More)
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2009
2009
Both the Ku subunit of the DNA-dependent protein kinase (DNA-PK) and the facilitator of chromatin transcription (FACT) complex… (More)
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2007
2007
Chlorambucil (CLB) treatment is used in chronic lymphocytic leukemia (CLL) but resistance to CLB develops in association with… (More)
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Highly Cited
2006
Highly Cited
2006
Poly (ADP-ribose) polymerase (PARP-1), ATM and DNA-dependent protein kinase (DNA-PK) are all involved in responding to DNA damage… (More)
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2005
2005
In this study we investigated the in vitro time dependence of radiosensitisation, pharmacokinetics and metabolism of NU7026, a… (More)
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Highly Cited
2004
Highly Cited
2004
We report for the first time the use of a selective small-molecule inhibitor of DNA repair to potentiate topoisomerase II (topo… (More)
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Highly Cited
2003
Highly Cited
2003
The DNA repair enzymes, DNA-dependent protein kinase (DNA-PK) and poly(ADP-ribose) polymerase-1 (PARP-1), are key determinants of… (More)
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