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NU 6027

Known as: NU-6027, NU6027 
 
National Institutes of Health

Papers overview

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2019
2019
Tuberculosis (TB) is a global health concern, and this situation has further worsened due to the emergence of drug-resistant… Expand
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2018
2018
Oxidative stress is a key mediator of neuronal death in acute brain injuries, such as epilepsy, trauma, and stroke. Although it… Expand
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2016
2016
The potent and selective cyclin‐dependent kinase 2 (CDK2) inhibitor NU6027 (6‐cyclohexylmethoxy‐5‐nitroso‐2,4‐diaminopyrimidine… Expand
2016
2016
The potent and selective Cyclin-Dependent Kinase 2 (CDK2) inhibitor NU6027 (6-cyclohexylmethoxy-5nitroso-2,4-diaminopyrimidine… Expand
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2014
2014
Trovafloxacin (TVX) is a drug that has caused idiosyncratic, drug-induced liver injury (IDILI) in humans. In a murine model of… Expand
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2013
2013
Substitution of the cyano-NNO-azoxy moiety (NC-N=(O)N-) for the nitroso group in NU6027, a potent and selective CDK2 inhibitor… Expand
Highly Cited
2011
Highly Cited
2011
Background:The ataxia telangiectasia mutated and Rad3-related kinase (ATR) has a key role in the signalling of stalled… Expand
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2003
2003
The cyclin dependent kinase (cdk) inhibitor NU6027, 4-cyclohexylmethoxy-5-nitroso-pyrimidine-2,6-diamine (IC(50) vs cdk1/cyclinB1… Expand
Highly Cited
2000
Highly Cited
2000
Substituted guanines and pyrimidines were tested as inhibitors of cyclin B1/CDK1 and cyclin A3/CDK2 and soaked into crystals of… Expand