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NSC606985

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2016
024620052016

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Camptothecin
analogs & derivatives

Related mentions per year

Related mentions per year

1965-2018
1960198020002020
NSC606985
Camptothecin
analogs & derivatives

Papers overview

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2016
2016
Dissociation of NSC606985 induces atypical ER-stress and cell death in prostate cancer cells.
Castration-resistant prostate cancer (CRPC) is a major cause of prostate cancer (Pca) death. Chemotherapy is able to improve the… (More)
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2010
2010
Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells.
The acidic leucine-rich nuclear phosphoprotein 32 (ANP32)B has been reported to regulate gene expression by acting as a histone… (More)
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2009
2009
NSC606985 induces apoptosis, exerts synergistic effects with cisplatin, and inhibits hypoxia-stabilized HIF-1alpha protein in human ovarian cancer cells.
The camptothecins, which target the intranuclear enzyme topoisomerase I, have advanced to the forefront of several areas of… (More)
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2009
2009
NDRG1 is down-regulated in the early apoptotic event induced by camptothecin analogs: the potential role in proteolytic activation of PKC delta and apoptosis.
We previously reported that NSC606985, a new camptothecin analog, induces apoptosis of acute myeloid leukemic cells, which is… (More)
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2009
2009
Protein kinase C-delta mediates down-regulation of heterogeneous nuclear ribonucleoprotein K protein: involvement in apoptosis induction.
We reported previously that NSC606985, a camptothecin analogue, induces apoptosis of acute myeloid leukemia (AML) cells through… (More)
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2008
2008
NSC606985, a novel camptothecin analog, induces apoptosis and growth arrest in prostate tumor cells
Prostate cancer is a major cause of cancer mortality in American males. Once prostate cancer has metastasized, there is currently… (More)
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2007
2007
Subcellular proteome analysis of camptothecin analogue NSC606985-treated acute myeloid leukemic cells.
We reported previously that NSC606985, a camptothecin analogue, induces apoptosis of acute myeloid leukemia (AML) cells through… (More)
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2007
2007
Therapeutic efficacy of NSC606985, a novel camptothecin analog, in a mouse model of acute promyelocytic leukemia.
Nanomolar concentrations of NSC606985, a novel camptothecin (CPT) analog, effectively induces apoptosis in vitro in acute myeloid… (More)
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2005
2005
Nanomolar concentration of NSC606985, a camptothecin analog, induces leukemic-cell apoptosis through protein kinase Cdelta-dependent mechanisms.
As a promising new class of anticancer drugs, camptothecins have advanced to the forefront of several areas of therapeutic and… (More)
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2005
2005
Nanomolar concentration of NSC606985, a camptothecin analog, induces leukemic-cell apoptosis through protein kinase C –dependent mechanisms
As a promising new class of anticancer drugs, camptothecins have advanced to the forefront of several areas of therapeutic and… (More)
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