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NSC-87877

National Institutes of Health

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Quinolines

Papers overview

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2017
2017
Identification of novel dual-specificity phosphatase 26 inhibitors by a hybrid virtual screening approach based on pharmacophore and molecular docking.
2017
2017
Fragment-based screening of the oncogenic protein tyrosine phosphatase SHP2
Protein tyrosine phosphatases represent a family of signalling enzymes with emerging therapeutic potential. The cytoplasmic… 
2015
2015
NSC-87877 inhibits DUSP26 function in neuroblastoma resulting in p53-mediated apoptosis
Dual specificity protein phosphatase 26 (DUSP26) is overexpressed in high-risk neuroblastoma (NB) and contributes to… 
2014
2014
WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1
Angiogenesis, one of the major routes for tumor invasion and metastasis represents a rational target for therapeutic intervention… 
2010
2010
Inhibitory effects of SHP2 blocker NSC-87877 on inflammatory pain and its underlying mechanisms
Aim To investigate the effects of Src Homology-2 domain-containing Phosphatase 2(SHP2) blocker NSC-87877 on inflammatory pain and… 
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