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NSC-112907
Known as:
NSC 112907
, NSC112907
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Tetrahydrouridine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Oral and intravenous pharmacokinetics of 5-fluoro-2′-deoxycytidine and THU in cynomolgus monkeys and humans
J. Holleran
,
J. Beumer
,
+7 authors
J. Eiseman
Cancer Chemotherapy and Pharmacology
2015
Corpus ID: 10255372
Introduction5-Fluoro-2′-deoxycytidine (FdCyd; NSC48006), a fluoropyrimidine nucleoside inhibitor of DNA methylation, is degraded…
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2012
2012
Abstract 3782: Plasma pharmacokinetics of fluorodeoxycytidine, downstream metabolites, and tetrahydrouridine after combined administration to cynomolgus monkeys
J. Beumer
,
J. Holleran
,
+4 authors
J. Eiseman
2012
Corpus ID: 72144971
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Introduction: 5-Fluoro-2′-deoxycytidine (FdCyd…
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2010
2010
Stability of 5-Fluoro-2′-deoxycytidine and Tetrahydrouridine in Combination
Duoli Guo
,
P. Myrdal
,
+4 authors
S. Yalkowsky
AAPS PharmSciTech
2010
Corpus ID: 30326312
In vivo, the DNA methyltransferase inhibitor, 5-fluoro-2′-deoxycytidine (FdCyd, NSC-48006), is rapidly converted to its unwanted…
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1975
1975
Enhancement by tetrahydrouridine (NSC-112907) of the oral activity of 5-azacytidine (NSC-102816) in L1210 leukemic mice.
G. Neil
,
T. Moxley
,
S. Kuentzel
,
R. Manak
,
L. Haňka
Cancer chemotherapy reports
1975
Corpus ID: 26229485
5-Azacytidine is more active when administered parenterally than orally in the treatment of L1210 leukemic mice. Oral…
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1975
1975
Inhibition of deamination of 14C-cytosine arabinoside (NSC-63878): a useful biologic assay for tetrahydrouridine (NSC-112907).
Furner Rl
,
Mellett Lb
1975
Corpus ID: 89167933
: Inhibition of the deamination of 14C-cytosine arabinoside by two lots of tetrahydrouridine was studied in monkey serum. The…
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1975
1975
Inhibition of deamination of 14C-cytosine arabinoside (NSC-63878): a useful biologic assay for tetrahydrouridine (NSC-112907).
R. Furner
,
L. B. Mellett
Cancer chemotherapy reports
1975
Corpus ID: 39963086
Inhibition of the deamination of 14C-cytosine arabinoside by two lots of tetrahydrouridine was studied in monkey serum. The…
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1974
1974
Preclinical toxicologic evaluation of tetrahydrouridine (NSC-112907) in beagle dogs and rhesus monkeys.
Goldenthal Ei
,
Cookson Km
,
Geil Rg
,
Wazeter Fx
1974
Corpus ID: 77385387
1974
1974
Preclinical toxicologic evaluation of tetrahydrouridine (NSC-112907) in beagle dogs and rhesus monkeys.
E. Goldenthal
,
K. M. Cookson
,
R. Geil
,
F. X. Wazeter
Cancer chemotherapy reports. Part 3
1974
Corpus ID: 8435214
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