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NSC-112907

Known as: NSC 112907, NSC112907 
 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Tetrahydrouridine

Papers overview

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2015
2015
Oral and intravenous pharmacokinetics of 5-fluoro-2′-deoxycytidine and THU in cynomolgus monkeys and humans
Introduction5-Fluoro-2′-deoxycytidine (FdCyd; NSC48006), a fluoropyrimidine nucleoside inhibitor of DNA methylation, is degraded… Expand
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2012
2012
Abstract 3782: Plasma pharmacokinetics of fluorodeoxycytidine, downstream metabolites, and tetrahydrouridine after combined administration to cynomolgus monkeys
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Introduction: 5-Fluoro-2′-deoxycytidine (FdCyd… Expand
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2010
2010
Stability of 5-Fluoro-2′-deoxycytidine and Tetrahydrouridine in Combination
In vivo, the DNA methyltransferase inhibitor, 5-fluoro-2′-deoxycytidine (FdCyd, NSC-48006), is rapidly converted to its unwanted… Expand
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1975
1975
Enhancement by tetrahydrouridine (NSC-112907) of the oral activity of 5-azacytidine (NSC-102816) in L1210 leukemic mice.
5-Azacytidine is more active when administered parenterally than orally in the treatment of L1210 leukemic mice. Oral… Expand
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1975
1975
Inhibition of deamination of 14C-cytosine arabinoside (NSC-63878): a useful biologic assay for tetrahydrouridine (NSC-112907).
Inhibition of the deamination of 14C-cytosine arabinoside by two lots of tetrahydrouridine was studied in monkey serum. The… Expand
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1975
1975
Inhibition of deamination of 14C-cytosine arabinoside (NSC-63878): a useful biologic assay for tetrahydrouridine (NSC-112907).
 
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1974
1974
Preclinical toxicologic evaluation of tetrahydrouridine (NSC-112907) in beagle dogs and rhesus monkeys.
 
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1974
1974
Preclinical toxicologic evaluation of tetrahydrouridine (NSC-112907) in beagle dogs and rhesus monkeys.
 
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