Tetrahydrouridine

Known as: 2(1H)-pyrimidinone, tetrahydro-4-hydroxy-1-beta-D-ribofuranosyl-, THU, Tetrahydrouridine [Chemical/Ingredient] 
A synthetic pyrimidine nucleoside analogue with biomodulating activity. Tetrahydrouridine increases the efficacy of the radiosensitizer cytochlor (5… (More)
National Institutes of Health

Papers overview

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2012
2012
The deoxycytidine analog decitabine (DAC) can deplete DNA methyl-transferase 1 (DNMT1) and thereby modify cellular epigenetics… (More)
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2011
2011
Inhibition of nitric oxide synthesis with N ω -nitro-l-arginine methyl ester (l-NAME) induces marked hypertension and oxidative… (More)
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2008
2008
PURPOSE In vivo, 2',2'-difluoro-2'-deoxycytidine (dFdC) is rapidly inactivated by gut and liver cytidine deaminase (CD) to 2',2… (More)
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2007
2007
Cytidine analogues such as cytosine arabinoside, gemcitabine, decitabine, 5-azacytidine, 5-fluoro-2′-deoxycytidine and 5-chloro-2… (More)
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2007
2007
Although the DNA methyltransferase inhibitor 5-fluoro-2′-deoxycytidine (FdCyd), is being evaluated clinically, it must be… (More)
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Highly Cited
1999
Highly Cited
1999
We have identified a novel gene referred to as activation-induced deaminase (AID) by subtraction of cDNAs derived from switch… (More)
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1999
1999
Translations into Vietnamese and Arabic of the Edinburgh Postnatal Depression Scale (EPDS) were assessed to determine usefulness… (More)
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1979
1979
In conventional clinical use, cytosine arabinoside (ara-C) is rapidly deaminated by pyrimidine nucleoside deaminase to the… (More)
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1975
1975
5-Azacytidine is more active when administered parenterally than orally in the treatment of L1210 leukemic mice. Oral… (More)
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