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NRAS NP_002515.1:p.G12X
Known as:
NP_002515.1 :p.Gly12Xxx
, GTPase NRas G12X
, NRAS p.Gly12Xxx
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A change in the amino acid residue at position 12 in the GTPase NRas protein where glycine has been replaced by another amino acid.
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
SP174 Antibody Lacks Specificity for NRAS Q61R and Cross-Reacts With HRAS and KRAS Q61R Mutant Proteins in Malignant Melanoma
Anna Felisiak-Golabek
,
Shingo Inaguma
,
+10 authors
M. Miettinen
Applied immunohistochemistry & molecular…
2018
Corpus ID: 13768058
HRAS, KRAS, and NRAS, highly homologous proteins, are often mutationally activated in cancer. Usually, mutations cluster in…
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2017
2017
Abstract LB-307: Dissecting mutual exclusiveness of oncogenic mutations in melanoma
Raj Kumar
,
C. Njauw
,
Zhenyu Ji
,
Anpuchchelvi Rajadurai
,
H. Tsao
2017
Corpus ID: 79642085
Mutual exclusiveness of oncogenes is a general phenomenon in cancer. Specifically in melanoma BRAF and NRAS mutations do not co…
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2016
2016
Distinct differences in metal ion specificity of RNA and DNA G-quadruplexes
Helena Guiset Miserachs
,
D. Donghi
,
R. Börner
,
S. Johannsen
,
R. Sigel
JBIC Journal of Biological Inorganic Chemistry
2016
Corpus ID: 254088313
RNA G-quadruplexes, as their well-studied DNA analogs, require the presence of cations to fold and remain stable. This is the…
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2016
2016
Abstract 301: Identification of NRAS isoform 2 overexpression as a novel mechanism facilitating BRAF inhibitor resistance in malignant melanoma (MM)
Megan C. Duggan
,
Andrew Stiff
,
+6 authors
W. Carson
2016
Corpus ID: 78825748
Activating mutations in BRAF are found in 50% of melanomas and are associated with poor outcomes due to constitutive activation…
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2016
2016
Untersuchungen zur Regulation und Bedeutung der Serinprotease HTRA1 in Tumorzellen
Kamilla Ripkens
2016
Corpus ID: 191179656
Die HtrA-Proteine (high temperature requirement A) gehoren zu einer Familie von hochkonservierten Serin-Proteasen, die sowohl…
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2015
2015
Endlich neue Therapieoptionen beim malignen Melanom
J. Tietze
,
C. Berking
Tumordiagnostik & Therapie
2015
Corpus ID: 256809110
Zusammenfassung Die Therapie des malignen Melanoms hat sich in den letzten Jahren grundlegend verändert. Als neue…
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2014
2014
Medikamentöse Systemtherapie des Melanoms
D. Schadendorf
,
H. Bernhard
Der Onkologe
2014
Corpus ID: 11614593
ZusammenfassungHintergrundJährlich erleiden rund 3000 Melanompatienten eine Disseminierung ihrer Erkrankung. Über mehr als 3…
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Review
2014
Review
2014
Endlich neue Therapieoptionen beim malignen Melanom
J. Tietze
,
C. Berking
Deutsche Medizinische Wochenschrift
2014
Corpus ID: 76504155
Zusammenfassung Die Therapie des malignen Melanoms hat sich in den letzten Jahren grundlegend verändert. Als neue…
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2014
2014
Augmentation du pourcentage d’allèles mutés NRAS pQ61K au cours de la progression d’un mélanome cutané métastatique
E. Funck-Brentano
,
Zofia Hélias-Rodzewicz
,
+4 authors
P. Saiag
2014
Corpus ID: 70565326
Review
2014
Review
2014
Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing
B. Durham
,
Jing Ma
,
+14 authors
O. Abdel-Wahab
2014
Corpus ID: 208407054
Systemic histiocytic disorders, including Langerhans cell histiocytosis (LCH) and the non-Langerhans cell histiocytic disorder…
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