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NR5A2 wt Allele

Known as: LRH-1, FTZ-F1, LRH1 
Human NR5A2 wild-type allele is located in the vicinity of 1q32.1 and is approximately 150 kb in length. This allele, which encodes nuclear receptor… 
National Institutes of Health

Related topics

Related topics

16 relations
1q32.1Biologic DevelopmentCell Differentiation processCell Proliferation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Ameliorative effect of vitamin E to mouse dams and their pups following exposure of mothers to chlorpyrifos during gestation and lactation periods
Pesticides are omnipresent in environment, water, fruits, and vegetables and are considered as risk factors for human health… 
2016
2016
BDE-47 causes developmental retardation with down-regulated expression profiles of ecdysteroid signaling pathway-involved nuclear receptor (NR) genes in the copepod Tigriopus japonicus.
2011
2011
Hemotoxicity Induced by Chronic Chlorpyrifos Exposure in Wistar Rats: Mitigating Effect of Vitamin C
The study evaluated the ameliorative effect of vitamin C on chronic chlorpyrifos-induced hematological alterations in Wistar rats… 
2009
2009
Subtoxic chlorpyrifos treatment resulted in differential expression of genes implicated in neurological functions and development
Chlorpyrifos (CPF), a commonly used organophosphorus insecticide, induces acetylcholinesterase inhibition and cholinergic… 
2009
2009
Biochemical alterations induced by the acute exposure to combination of chlorpyrifos and lead in Wistar rats.
Chlorpyrifos, a well known organophosphorus insecticide and heavy metal lead, was challenged to Wistar rats to study their… 
Highly Cited
2007
Highly Cited
2007
Increased expression of hLRH-1 in human gastric cancer and its implication in tumorigenesis
Altered signaling pathways or deregulated transcription factors represent an important category of molecular events leading to… 
2007
2007
The effect of route, vehicle, and divided doses on the pharmacokinetics of chlorpyrifos and its metabolite trichloropyridinol in neonatal Sprague-Dawley rats.
There is a paucity of data on neonatal systemic exposure using different dosing paradigms. Male CD (Sprague-Dawley derived) rats… 
2005
2005
Zebrafish ftz-f1a (nuclear receptor 5a2) functions in skeletal muscle organization.
2001
2001
The mouse fetoprotein transcription factor (FTF) gene promoter is regulated by three GATA elements with tandem E box and Nkx motifs, and FTF in turn activates the Hnf3beta, Hnf4alpha, and Hnf1alpha…
Fetoprotein transcription factor (FTF) is an orphan nuclear receptor that activates the alpha(1)-fetoprotein gene during early… 
2001
2001
Segmentation gene product Fushi tarazu is an LXXLL motif-dependent coactivator for orphan receptor FTZ-F1
Orphan receptors for whom cognate ligands have not yet been identified form a large subclass within the nuclear receptor… 
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