NR5A2 wt Allele

Known as: LRH-1, FTZ-F1, LRH1 
Human NR5A2 wild-type allele is located in the vicinity of 1q32.1 and is approximately 150 kb in length. This allele, which encodes nuclear receptor… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) by expressing four transcription factors: Oct4, Sox2… (More)
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Highly Cited
2010
Highly Cited
2010
The orphan receptor LRH-1 and the oxysterol receptors LXRalpha and LXRbeta are established transcriptional regulators of lipid… (More)
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Highly Cited
2008
Highly Cited
2008
Female fertility requires normal ovarian follicular growth and ovulation. The nuclear receptor liver receptor homolog 1 has been… (More)
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Highly Cited
2005
Highly Cited
2005
Oct4 plays an essential role in maintaining the inner cell mass and pluripotence of embryonic stem (ES) cells. The expression of… (More)
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Highly Cited
2004
Highly Cited
2004
LRH-1 is an orphan nuclear receptor predominantly expressed in tissues of endodermal origin, where it controls development and… (More)
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Highly Cited
2003
Highly Cited
2003
Fetal and childhood exposures to widely used organophosphate pesticides, especially chlorpyrifos (CPF), have raised concerns… (More)
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Highly Cited
2002
Highly Cited
2002
Use of chlorpyrifos (CPF) has been curtailed due to its developmental neurotoxicity. In rats, postnatal CPF administration… (More)
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Highly Cited
1999
Highly Cited
1999
The acquisition of competence is a key mechanism for refining global signals to distinct spatial and temporal responses. The… (More)
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Highly Cited
1999
Highly Cited
1999
Cholesterol 7alpha-hydroxylase is the first and rate-limiting enzyme in a pathway through which cholesterol is metabolized to… (More)
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Highly Cited
1993
Highly Cited
1993
Highly degenerate PCR primers were designed based on the amino acid sequence of the zinc finger motifs of known nuclear receptor… (More)
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