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NR4A1 gene

Known as: NR4A1, NP10, NGFIB 
This gene is involved in the induction of apoptosis. It also plays a role in regulation of transcription.
National Institutes of Health

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Related topics

14 relations
Biologic DevelopmentCell Differentiation processCell ProliferationHomeostasis

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NR4A1 wt Allele

Papers overview

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Highly Cited
2012
Highly Cited
2012
Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status
Objective There is increasing interest in adding common genetic variants identified through genome wide association studies (GWAS… 
Highly Cited
2007
Highly Cited
2007
The Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor (SMRT) Corepressor Is Required for Full Estrogen Receptor α Transcriptional Activity
ABSTRACT Multiple factors influence estrogen receptor α (ERα) transcriptional activity. Current models suggest that the silencing… 
Highly Cited
2005
Highly Cited
2005
Human THAP7 Is a Chromatin-associated, Histone Tail-binding Protein That Represses Transcription via Recruitment of HDAC3 and Nuclear Hormone Receptor Corepressor*
The identities of signal transducer proteins that integrate histone hypoacetylation and transcriptional repression are largely… 
Highly Cited
2002
Highly Cited
2002
Chromatin Disruption and Histone Acetylation in Regulation of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat by Thyroid Hormone Receptor
ABSTRACT The human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) controls the expression of HIV-1 viral genes… 
Highly Cited
2001
Highly Cited
2001
Episodic evolution of growth hormone in primates and emergence of the species specificity of human growth hormone receptor.
Growth hormone (GH) evolution is very conservative among mammals, except for primates and ruminant artiodactyls. In fact, most… 
Highly Cited
1997
Highly Cited
1997
Mapping of a Cytoplasmic Domain of the Human Growth Hormone Receptor That Regulates Rates of Inactivation of Jak2 and Stat Proteins*
It has been previously demonstrated that growth hormone (GH)-stimulated tyrosine phosphorylation of Jak2 and Stat5a and Stat5b… 
Highly Cited
1997
Highly Cited
1997
Prominent expression of nuclear hormone receptor RORα in Purkinje cells from early development
Highly Cited
1990
Highly Cited
1990
The human Na, K-ATPase alpha 1 gene: characterization of the 5'-flanking region and identification of a restriction fragment length polymorphism.
Highly Cited
1990
Highly Cited
1990
Mutational analysis identifies a new functional domain of the thyroid hormone receptor.
We studied the functional significance of a region of the thyroid hormone receptor ligand binding domain which is conserved in… 
Highly Cited
1988
Highly Cited
1988
Characterization of a third human thyroid hormone receptor coexpressed with other thyroid hormone receptors in several tissues.
A cDNA that encodes a third type of human thyroid hormone receptor (hTR alpha 1) has been isolated from a skeletal muscle library… 
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