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NR3C1 gene

Known as: NUCLEAR RECEPTOR SUBFAMILY 3, GROUP C, MEMBER 1, GRL, GR 
This gene is involved in ligand-activated transcriptional regulation and mutations in the gene are associated with glucocorticoid resistance.
National Institutes of Health

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Related topics

16 relations
Biologic DevelopmentCell Differentiation processCell ProliferationGlucocorticoid Receptor

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NR3C1 wt Allele

Papers overview

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2018
2018
Topological data analysis (TDA) of U-BIOPRED paediatric peripheral blood gene expression identified asthma phenotypes characterised by alternative splicing of glucocorticoid receptor (GR) mRNA
Background: Molecular stratification of childhood asthma could enable targeted therapy.Aims: Unbiased analysis of gene expression… 
2016
2016
Glucocorticoid combined with hyaluronic acid enhance glucocorticoid receptor activity through inhibiting p-38MAPK signal pathway activation in treating acute lung injury in rats.
OBJECTIVE In order to seek an effective strategy for clinical treatment of acute lung injury (ALI), we are committed to explore… 
2010
2010
BTG 1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia
Resistance to glucocorticoids (GCs) is a major clinical problem in the treatment of acute lymphoblastic leukemia (ALL), but the… 
2009
2009
Recruitment of chromatin remodelling factors during gene activation via the glucocorticoid receptor N-terminal domain
We have shown that yeast mutants with defects in the Ada adaptor proteins are defective in hormonedependent gene activation by… 
2006
2006
Potential advantage of N 363 S glucocorticoid receptor polymorphism in 21-hydroxylase deficiency
Objective: Congenital adrenal hyperplasia (CAH) shows a range of severity which is explained in part by the different mutations… 
2005
2005
A Template-Based Analysis of GRL: Chapter 8
2001
2001
The Responses of Rat Liver Glucocorticoid Receptors and Genes for Tyrosine Aminotransferase, Alpha-2-Macroglobulin and Gamma-Fibrinogen to Adrenalectomy-, Dexamethasone- and Inflammation-Induced…
The responses of liver glucocorticoid receptor (GR) and genes coding for a glucocorticoid-inducible tyrosine aminotransferase… 
1986
1986
Hormone dependency of transformation of rat liver glucocorticoid receptor in vitro: effects of heat, salt, and nucleotides.
A majority of the untransformed glucocorticoid-receptor complexes (GRc) from rat liver cytosol sedimented in the 9S region in 5… 
1984
1984
[Study of morphological types of nephrotic glomerulonephritis and the number of glucocorticoid receptors of lymphocytes for prognosis of the effectiveness of glucocorticoid therapy].
The study of the glucocortocoid receptors (GCR) level of blood lymphocytes in 31 patients with glomerulonephritis (GN) of the… 
1982
1982
Identification of modified forms of human glucocorticoid receptors during the cell cycle.
Glucocorticoids induce alkaline phosphatase activity in HeLa S3 cells only during the Late G1 and S phases of the cell cycle. In…