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NR2C2 gene

Known as: NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 2, TAK1, Nuclear Receptor Subfamily 2, Group C, Member 2 Gene 
This gene is involved in hormone-dependent transcriptional regulation.
National Institutes of Health

Related topics

Related topics

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Biologic DevelopmentCell Differentiation processCell ProliferationHomeostasis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
TR4 nuclear receptor promotes clear cell renal cell carcinoma (ccRCC) vasculogenic mimicry (VM) formation and metastasis via altering the miR490-3p/vimentin signals
While TR4 nuclear receptor plays key roles to promote prostate cancer progression, its roles to alter the progression of clear… 
2012
2012
Inducible HSP70 Antagonizes IL-1β Cytocidal Effects through Inhibiting NF-kB Activation via Destabilizing TAK1 in HeLa Cells
Background Despite several reports describing the HSP70-mediated cytoprotection against IL-1, the precise mechanism for this… 
2011
2011
Premature aging with impaired oxidative stress defense in mice lacking TR4.
Early studies suggest that TR4 nuclear receptor is a key transcriptional factor regulating various biological activities… 
2003
2003
Suppression of Hepatitis B Virus Core Promoter by the Nuclear Orphan Receptor TR4*
The TR4 orphan receptor is a member of the nuclear receptor superfamily that modulates gene expression via binding to the AGGTCA… 
2003
2003
Disruption of TR4 Orphan Nuclear Receptor Reduces the Expression of Liver Apolipoprotein E/C-I/C-II Gene Cluster*
Apolipoprotein E (apoE) is synthesized in many tissues, and the liver is the primary site from which apoE redistributes… 
2003
2003
Identification of a Novel Testicular Orphan Receptor-4 (TR4)-associated Protein as Repressor for the Selective Suppression of TR4-mediated Transactivation*
Although many co-activators have been identified for various nuclear receptors, relatively fewer co-repressors have been isolated… 
Review
2002
Review
2002
Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily
Highly Cited
1997
Highly Cited
1997
Identification of Direct Repeat 4 as a Positive Regulatory Element for the Human TR4 Orphan Receptor
While the TR4 orphan receptor (TR4) is able to repress the expression of its target genes via its interaction with the direct… 
Highly Cited
1997
Highly Cited
1997
Induction of the Intronic Enhancer of the Human Ciliary Neurotrophic Factor Receptor (CNTFRα) Gene by the TR4 Orphan Receptor
A conserved hormone response element, CNTFR-DR1 (5′-GGG-3′), has been identified in the 5th intron of the α component of the… 
Highly Cited
1995
Highly Cited
1995
Suppression of Gene Expression on the Simian Virus 40 Major Late Promoter by Human TR4 Orphan Receptor
The key expression of the simian virus 40 (SV40) major late promoter could be repressed by the human TR4 orphan receptor via the… 
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