NR1I3 gene

Known as: constitutive androstane receptor, CONSTITUTIVE ANDROSTANE RECEPTOR, BETA, CAR-BETA 
This gene is involved in both drug metabolism and bilirubin clearance.
National Institutes of Health

Papers overview

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2009
2009
The nuclear receptor constitutive androstane receptor (CAR) (NR1I3) regulates hepatic genes involved in xenobiotic detoxification… (More)
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2008
2008
Activating transcription factor (ATF) 5 is a member of the ATF/cAMP response element-binding protein family, which has been… (More)
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Highly Cited
2007
Highly Cited
2007
In our study, we tested the hypothesis whether valproic acid (VPA) in therapeutic concentrations has potential to affect… (More)
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Highly Cited
2005
Highly Cited
2005
The constitutive androstane receptor (CAR) mediates the hepatic induction of various xenobiotic metabolizing enzymes and… (More)
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Highly Cited
2004
Highly Cited
2004
Cytosolic sulfotransferase (SULT)-mediated sulfation plays an essential role in the detoxification of bile acids and is necessary… (More)
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Highly Cited
2003
Highly Cited
2003
The orphan nuclear constitutive androstane receptor (CAR) is proposed to play a central role in the response to xenochemical… (More)
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2003
2003
The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) mediate the expression of mammalian cytochrome p450… (More)
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Highly Cited
2002
Highly Cited
2002
The multidrug resistance-associated protein 2 (MRP2, ABCC2), mediates the efflux of several conjugated compounds across the… (More)
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Highly Cited
2002
Highly Cited
2002
The CYP2C subfamily metabolizes many clinically important drugs. These genes respond to prototypical inducers such as… (More)
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Highly Cited
2002
Highly Cited
2002
The NR1I subfamily of nuclear receptors contains a phylogenetically diverse array of receptors related to the mammalian pregnane… (More)
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