NPHS2 protein

Known as: podocin 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Mutant forms of TRPC6 can activate NFAT-dependent transcription in vitro via calcium influx and activation of calcineurin. The… (More)
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Highly Cited
2008
Highly Cited
2008
Nephrin is a slit diaphragm protein critical for structural and functional integrity of visceral glomerular epithelial cells… (More)
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Highly Cited
2008
Highly Cited
2008
Urinary exosomes are excreted from all nephron segments and constitute a rich source of intracellular kidney injury biomarkers… (More)
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Highly Cited
2008
Highly Cited
2008
In preeclampsia (PE), proteinuria has been associated with a reduced expression of nephrin by podocytes. In the present study, we… (More)
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Highly Cited
2007
Highly Cited
2007
IL-13 has been implicated in the pathogenesis of minimal-change nephrotic syndrome. This study aimed to investigate the role of… (More)
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Highly Cited
2007
Highly Cited
2007
Accumulating evidence suggests that mineralocorticoid receptor blockade effectively reduces proteinuria in hypertensive patients… (More)
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Highly Cited
2003
Highly Cited
2003
Hereditary nephrotic syndrome is a heterogeneous disease, characterized by heavy proteinuria and renal failure. Mutations of… (More)
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Highly Cited
2003
Highly Cited
2003
Mutations of NPHS1 or NPHS2, the genes encoding for the glomerular podocyte proteins nephrin and podocin, cause steroid-resistant… (More)
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Highly Cited
2002
Highly Cited
2002
Recent molecular insights have established the podocyte as a key component of the glomerular filtration barrier, and hence an… (More)
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Highly Cited
2001
Highly Cited
2001
NPHS2 was recently identified as a gene whose mutations cause autosomal recessive steroid-resistant nephrotic syndrome. Its… (More)
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