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NPC 15437

Known as: Hexanamide, 2,6-diamino-N-((1-(1-oxotridecyl)-2-piperidinyl)methyl)-, NPC-15437 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Piperidines

Papers overview

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Highly Cited
2012
Highly Cited
2012
Capsaicin mediates apoptosis in human nasopharyngeal carcinoma NPC-TW 039 cells through mitochondrial depolarization and endoplasmic reticulum stress
Capsaicin, a pungent compound found in hot chili peppers, has been reported to have antitumor activities in many human cancer… 
Highly Cited
2010
Highly Cited
2010
Mechanisms of endothelium-dependent vasodilation in male and female, young and aged offspring born growth restricted.
Numerous epidemiological studies have shown that cardiovascular dysfunction in adult life may be programmed by compromised growth… 
Highly Cited
2007
Highly Cited
2007
Soluble Epoxide Hydrolase: A Novel Therapeutic Target in Stroke
The P450 eicosanoids epoxyeicosatrienoic acids (EETs) are produced in brain and perform important biological functions, including… 
2006
2006
Contribution of epoxyeicosatrienoic acids to the hypoxia-induced activation of Ca2+-activated K+ channel current in cultured rat hippocampal astrocytes
Highly Cited
2004
Highly Cited
2004
Ergosterol elicits oxidative burst in tobacco cells via phospholipase A2 and protein kinase C signal pathway.
Highly Cited
2002
Highly Cited
2002
Human urotensin II-induced aorta ring contractions are mediated by protein kinase C, tyrosine kinases and Rho-kinase: inhibition by somatostatin receptor antagonists.
2001
2001
Epoxyeicosatrienoic Acid–Mediated Renal Vasodilation to Arachidonic Acid Is Enhanced in SHR
We tested the hypothesis that cyclooxygenase-independent vasodilation produced by arachidonic acid (AA) is mediated by… 
Highly Cited
2000
Highly Cited
2000
Cytochrome P450 and cyclooxygenase metabolites contribute to the endothelin-1 afferent arteriolar vasoconstrictor and calcium responses.
Arachidonic acid metabolites contribute to the endothelin-1 (ET-1)-induced decrease in renal blood flow, but the vascular sites… 
Highly Cited
2000
Highly Cited
2000
P-450 epoxygenase and NO synthase inhibitors reduce cerebral blood flow response to N-methyl-D-aspartate.
Epoxyeicosatrienoic acids are cerebral vasodilators produced in astrocytes by cytochrome P-450 epoxygenase activity. The P-450… 
Highly Cited
1999
Highly Cited
1999
Contribution of cytochrome P450 epoxygenase and hydroxylase pathways to afferent arteriolar autoregulatory responsiveness
Previous studies have demonstrated an important role for the cytochrome P450 (CYT‐P450) pathway in afferent arteriole… 
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