NOX1 gene

Known as: NADPH OXIDASE HOMOLOG 1, GP91-2, NADPH OXIDASE 1 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
NADPH oxidases are major sources of superoxide (O2*-) and hydrogen peroxide (H2O2) in vascular cells. Production of these… (More)
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Highly Cited
2007
Highly Cited
2007
Tumor necrosis factor (TNF) is an important cytokine in immunity and inflammation and induces many cellular responses, including… (More)
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Highly Cited
2006
Highly Cited
2006
To understand the role of the superoxide-generating NADPH oxidase NOX1 in the vascular system, we have generated NOX1-deficient… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Increased production of reactive oxygen species (ROSs) by angiotensin II (Ang II) is involved in the initiation and… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Reactive oxygen species (ROS) have been implicated in the development of cardiovascular pathologies. NAD(P)H oxidases… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Reactive oxygen species (ROS) that act as signaling molecules in vascular smooth muscle cells (VSMC) and contribute to… (More)
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Highly Cited
2003
Highly Cited
2003
NOX1, an NADPH oxidase expressed predominantly in colon epithelium, shows a high degree of similarity to the phagocyte NADPH… (More)
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Highly Cited
2002
Highly Cited
2002
The reactive oxygen-generating enzyme Nox1 transforms NIH 3T3 cells, rendering them highly tumorigenic and, as shown herein, also… (More)
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Highly Cited
2001
Highly Cited
2001
Emerging evidence indicates that reactive oxygen species are important regulators of vascular function. Although NAD(P)H oxidases… (More)
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Highly Cited
2001
Highly Cited
2001
Nox1, a homologue of gp91phox, the catalytic moiety of the superoxide (O(2)(-))-generating NADPH oxidase of phagocytes, causes… (More)
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