NOS activity (molecular function)

Known as: N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming), nopaline dehydrogenase activity, nopaline synthase activity 
Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH. [EC:1.5.1.19, MetaCyc:D… (More)

Topic mentions per year

Topic mentions per year

1985-2017
010020019852017

Papers overview

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Highly Cited
2005
Highly Cited
2005
Cardiac pressure load stimulates hypertrophy, often leading to chamber dilation and dysfunction. ROS contribute to this process… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Although abnormal L-arginine NO signaling contributes to endothelial dysfunction in the aging cardiovascular system… (More)
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Highly Cited
1999
Highly Cited
1999
The goal of this study was to interrogate the role of inducible NO synthase (iNOS) in the late phase of ischemic preconditioning… (More)
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Highly Cited
1996
Highly Cited
1996
Endothelial nitric-oxide synthase (eNOS) generates the key signaling molecule nitric oxide in response to intralumenal hormonal… (More)
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Highly Cited
1996
Highly Cited
1996
Tetracyclines have recently been shown to have "chondroprotective" effects in inflammatory arthritides in animal models. Since… (More)
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Highly Cited
1994
Highly Cited
1994
Cyclooxygenase (COX) converts arachidonic acid to prostaglandin H2, which is further metabolized to prostanoids. Two isoforms of… (More)
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Highly Cited
1994
Highly Cited
1994
We have examined the effects of pregnancy and sex hormones on calcium-dependent and calcium-independent nitric oxide synthases… (More)
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Highly Cited
1994
Highly Cited
1994
Histochemical activity and immunoreactivity of nitric oxide synthase (NOS, EC 1.14.13.39) have been recently demonstrated in… (More)
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Highly Cited
1994
Highly Cited
1994
Nitric oxide (NO) produced by murine macrophages is important in murine resistance to ectromelia virus, herpes simplex virus, and… (More)
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Highly Cited
1993
Highly Cited
1993
Nitric oxide is a short-lived biologic mediator for diverse cell types. Synthesis of an inducible nitric oxide synthase (NOS) in… (More)
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