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NLRP1 inflammasome complex

Known as: NALP1 inflammasome complex, NALP1 inflammasome complex location, NLRP1 inflammasome complex location 
A protein complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Inflammasome activation is required for human rhinovirus-induced airway inflammation in naive and allergen-sensitized mice
Activation of the inflammasome is a key function of the innate immune response that regulates inflammation in response to… Expand
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Review
2018
Review
2018
The Crosstalk between Nrf2 and Inflammasomes
The Nrf2 (nuclear factor E2-related factor or nuclear factor (erythroid-derived 2)-like 2) transcription factor is a key player… Expand
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Review
2018
Review
2018
Photoaging and skin cancer: Is the inflammasome the missing link?
Photoaging and epithelial skin tumorigenesis are complex processes triggered mainly by UV radiation from chronic sun exposure… Expand
2018
2018
O receptor NLRP1 atua como um regulador do perfil de resposta Th17 em modelos experimentais e em humanos com diabetes tipo 1
 
Highly Cited
2017
Highly Cited
2017
The Pathogenic Role of NLRP3 Inflammasome Activation in Inflammatory Bowel Diseases of Both Mice and Humans
Background and Aims NLRP3 inflammasome is known to be involved in inflammatory bowel diseases. However, it is controversial… Expand
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Highly Cited
2016
Highly Cited
2016
The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease
BackgroundInterleukin-1 beta (IL-1β) and its key regulator, the inflammasome, are suspected to play a role in the… Expand
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Highly Cited
2016
Highly Cited
2016
IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis
Dysregulated inflammasome activation contributes to respiratory infections and pathologic airway inflammation. Through basic and… Expand
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2016
2016
The Influence of Radiotherapy on AIM2 Inflammasome in Radiation Pneumonitis
This study aims to investigate the influence of radiotherapy on absent in melanoma 2 (AIM2) inflammasome in radiation pneumonitis… Expand
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2015
2015
NLRP1 L155H Polymorphism is a Risk Factor for Preeclampsia Development
Augmented levels of IL‐1ß have been pointed out as an important pathogenic factor for preeclampsia development. Inflammasome is… Expand
Review
2009
Review
2009
The Inflammasomes
Innate immune cells such as macrophages and dendritic cells produce potent inflammatory cytokines to mount an appropriate immune… Expand
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