FAQ

NLRP1 inflammasome complex

Known as: NALP1 inflammasome complex, NALP1 inflammasome complex location, NLRP1 inflammasome complex location 
A protein complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2017
0120102017

Papers overview

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2017
2017
Association between NLPR1, NLPR3, and P2X7R Gene Polymorphisms with Partial Seizures
Objectives. Clinical and experimental evidence has clarified that the inflammatory processes within the brain play a pivotal role… (More)
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2014
2014
Distinct contributions of interleukin-1α (IL-1α) and IL-1β to innate immune recognition of Pseudomonas aeruginosa in the lung.
The bacterial pathogen Pseudomonas aeruginosa causes acute infections associated with significant morbidity and mortality. P… (More)
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2013
2013
Association of NLRP1 genetic variants and mRNA overexpression with generalized vitiligo and disease activity in a Gujarat population.
BACKGROUND It has been suggested that NLRP1 is involved in susceptibility to a wide range of autoimmune diseases including… (More)
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2012
2012
Human Monocytes Activates the NLRP3 Inflammasome in U1-Small Nuclear Ribonucleoprotein
The NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome is a caspase-1–containing cytosolic protein complex… (More)
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Highly Cited
2010
Highly Cited
2010
Host-Detrimental Role of Esx-1-Mediated Inflammasome Activation in Mycobacterial Infection
The Esx-1 (type VII) secretion system is a major virulence determinant of pathogenic mycobacteria, including Mycobacterium… (More)
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