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NLRP1 inflammasome complex

Known as: NALP1 inflammasome complex, NALP1 inflammasome complex location, NLRP1 inflammasome complex location 
A protein complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Inflammasome activation is required for human rhinovirus-induced airway inflammation in naive and allergen-sensitized mice
Activation of the inflammasome is a key function of the innate immune response that regulates inflammation in response to… 
2018
2018
O receptor NLRP1 atua como um regulador do perfil de resposta Th17 em modelos experimentais e em humanos com diabetes tipo 1
2018
2018
Inflammasome and Caspase-1 Activity Characterization and Evaluation: An Imaging Flow Cytometer–Based Detection and Assessment of Inflammasome Specks and Caspase-1 Activation
Inflammasome dysregulation is a hallmark of various inflammatory diseases. Evaluating inflammasome-associated structures (ASC… 
2016
2016
Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets
Tissue damage is usually regarded as a necessary price to pay for successful elimination of pathogens by the innate immune… 
2015
2015
NLRP1 L155H Polymorphism is a Risk Factor for Preeclampsia Development
Augmented levels of IL‐1ß have been pointed out as an important pathogenic factor for preeclampsia development. Inflammasome is… 
2015
2015
The Molecular Basis of Acute Cystitis; IL-1beta and Inflammasome Dysregulation
2013
2013
NLRP1 haplotypes associated with leprosy in Brazilian patients.
2012
2012
Cytosolic DNA Triggers Mitochondrial Apoptosis via DNA Damage Signaling Proteins Independently of AIM2 and RNA Polymerase III
A key host response to limit microbial spread is the induction of cell death when foreign nucleic acids are sensed within… 
Review
2009
Review
2009
The Inflammasomes
Innate immune cells such as macrophages and dendritic cells produce potent inflammatory cytokines to mount an appropriate immune… 
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