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NEK6 gene

Known as: SID6-1512, NEK6, NIMA-RELATED KINASE 6 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Discovery of a Selective NEK6 Kinase Inhibitor by Virtual Screening
NIMA-related kinases (Neks) are a conserved serine/threonine protein kinase family related tocell cycle progression and cell… 
2018
2018
MiR-506-3p inhibits cell proliferation, induces cell cycle arrest and apoptosis in retinoblastoma by directly targeting NEK6.
MicroRNAs (miRs) have been reported to participate in the initiation and progression of retinoblastoma (RB), as the most common… 
2016
2016
NEK6‐mediated phosphorylation of human TPP1 regulates telomere length through telomerase recruitment
Shelterin component TPP1 plays critical roles in chromosome end protection and telomere length regulation. Specifically, TPP1… 
2015
2015
Nek 6 and Hif-1 α cooperate with the cytoskeletal gateway of drug resistance to drive outcome in serous ovarian cancer
Hypoxia selects the most aggressive and drug-resistant clones in solid malignancies. One of the pivotal transcription factors… 
2015
2015
Abstract 4327: Nek6 and Hif-1α cooperate with the cytoskeletal gateway of drug resistance to drive outcome in serous ovarian cancer
Hypoxia selects the most aggressive and drug-resistant clones in solid malignancies. One of the pivotal transcription factors… 
2012
2012
Abstract 222: NEK6 promotes JB6 C141 cell transformation and activates STAT3 through its phosphorylation on Ser727
Highly Cited
2011
Highly Cited
2011
RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility.
RKIP-1 is a metastasis suppressor that is frequently downregulated in aggressive cancers. However, the consequences of RKIP loss… 
2011
2011
Linking Nek6 to p53-induced senescence
Comment on: Jee HJ, et al. Cell Cycle 2010; 9:4703–10. 
2011
2011
A role for Nek6 kinase activity in preventing senescence?
Comment on: Jee HJ, et al. Cell Cycle 2010; 9:4703–10. 
2003
2003
Differential control of the NIMA-related kinases, Nek6 and Nek7, by serum stimulation.
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