NEK11 gene

Known as: NIMA related kinase 11, NIMA-RELATED KINASE 11, NEVER IN MITOSIS GENE A-RELATED KINASE 11 
 
National Institutes of Health

Papers overview

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2017
2017
Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1
The cell-surface heparan sulfate proteoglycan syndecan-1 is important for tumor cell proliferation, migration, and cell cycle… (More)
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2016
2016
Nek11 regulates asymmetric cell division during mouse oocyte meiotic maturation.
Nek11, a member of the never in mitosis gene A (NIMA) family, is activated in somatic cells associated with G1/S or G2/M arrest… (More)
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2015
2015
Loss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging Agents
The Nek11 kinase is a potential mediator of the DNA damage response whose expression is upregulated in early stage colorectal… (More)
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2015
2015
Characterization and function of the nek11 kinase in cancer cells
The human serine/threonine NIMA-related protein kinase family comprises eleven members, named Nek1 to Nek11. Of these, Nek1, Nek4… (More)
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2014
2014
Downregulation of NEK11 is associated with drug resistance in ovarian cancer.
NEKs [NIMA (never in mitosis gene A)-related expressed kinase] are involved in ovarian cancer development and progression, while… (More)
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2010
2010
NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling.
The DNA damage induced G(2)/M checkpoint is an important guardian of the genome that prevents cell division when DNA lesions are… (More)
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Highly Cited
2009
Highly Cited
2009
NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint
DNA damage-induced cell-cycle checkpoints have a critical role in maintaining genomic stability. A key target of the checkpoints… (More)
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2008
2008
26 Critical role of NEK11 kinase in the IR-induced G2 checkpoint
 
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2004
2004
Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells.
We previously reported that Nek11, a member of the NIMA (never-in-mitosis A) family of kinases, is activated in G(1)/S-arrested… (More)
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2002
2002
Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses.
DNA replication and genotoxic stresses activate various checkpoint-associated protein kinases, and checkpoint dysfunction often… (More)
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