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NE 58051

Known as: NE-58051 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

DiphosphonatesPyridines

Papers overview

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2011
2011
Nitrogen-containing bisphosphonates can inhibit angiogenesis in vivo without the involvement of farnesyl pyrophosphate synthase.
Nitrogen-containing bisphosphonates (N-BPs) are widely used to block bone destruction associated with bone metastasis because… Expand
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2010
2010
How do bisphosphonates inhibit bone metastasis in vivo?
Bisphosphonates are potent inhibitors of osteoclast-mediated bone resorption and have demonstrated clinical utility in the… Expand
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Highly Cited
2000
Highly Cited
2000
Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases.
The molecular mechanisms by which tumor cells metastasize to bone are likely to involve invasion, cell adhesion to bone, and the… Expand
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Highly Cited
1997
Highly Cited
1997
Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices.
The molecular mechanisms by which tumor cells induce osteolytic metastases are likely to involve tumor cell adhesion to bone as… Expand
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