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NCX1000
Known as:
NCX 1000
, NCX-1000
National Institutes of Health
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Papers overview
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2010
2010
NCX-1000, a Nitric Oxide–Releasing Derivative of UDCA, Does Not Decrease Portal Pressure in Patients With Cirrhosis: Results of a Randomized, Double-Blind, Dose-Escalating Study
A. Berzigotti
,
P. Bellot
,
+4 authors
J. Bosch
The American Journal of Gastroenterology
2010
Corpus ID: 2253296
OBJECTIVES:NCX-1000 (2(acetyloxy) benzoic acid-3(nitrooxymethyl)phenyl ester) is an nitric oxide (NO)-releasing derivative of…
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Review
2008
Review
2008
Organization of the core structure of the postsynaptic density (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, 11 (4453-4458) DOI: 10.1073/pnas.0800897105…
Xiaobing Chen
,
C. Winters
,
+4 authors
T. Reese
2008
Corpus ID: 9416853
EDITORIAL EXPRESSION OF CONCERN. PNAS is publishing an Editorial Expression of Concern regarding the following three articles: (i…
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2007
2007
Combining ursodeoxycholic acid or its NO-releasing derivative NCX-1000 with lipophilic antioxidants better protects mouse hepatocytes against amiodarone toxicity.
A. Ouazzani-Chahdi
,
A. Elimadi
,
A. Chabli
,
J. Spénard
,
P. Colin
,
P. Haddad
Canadian journal of physiology and pharmacology
2007
Corpus ID: 21945492
Nonalcoholic steatohepatitis (NASH) is a common and potentially severe form of liver disease. This study aimed to determine the…
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2004
2004
Liver delivery of NO by NCX‐1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice THIS ARTICLE HAS BEEN RETRACTED
S. Fiorucci
,
E. Antonelli
,
+4 authors
A. Morelli
British journal of pharmacology
2004
Corpus ID: 27728227
NCX‐1000, (3α, 5β, 7β)‐3,7‐dihydroxycholan‐24oic acid[2‐methoxy‐4‐[3‐[4‐(nitroxy)butoxy]‐3‐oxo‐1‐propenyl]phenyl ester, is a…
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Review
2004
Review
2004
Treatment of portal hypertension with NCX-1000, a liver-specific NO donor. A review of its current status.
S. Fiorucci
,
E. Antonelli
,
P. Tocchetti
,
A. Morelli
Cardiovascular drug reviews
2004
Corpus ID: 24208943
Portal hypertension, a life threatening complication of liver cirrhosis, results from increased intrahepatic resistance and…
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Highly Cited
2003
Highly Cited
2003
NCX-1000, a nitric oxide-releasing derivative of ursodeoxycholic acid, ameliorates portal hypertension and lowers norepinephrine-induced intrahepatic resistance in the isolated and perfused rat liver…
S. Fiorucci
,
E. Antonelli
,
+8 authors
A. Morelli
Journal of hepatology
2003
Corpus ID: 22892114
Highly Cited
2003
Highly Cited
2003
A liver-specific nitric oxide donor improves the intra-hepatic vascular response to both portal blood flow increase and methoxamine in cirrhotic rats.
M. Loureiro-Silva
,
G. Cadelina
,
Y. Iwakiri
,
R. Groszmann
Journal of hepatology
2003
Corpus ID: 24614212
Highly Cited
2001
Highly Cited
2001
NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension
S. Fiorucci
,
E. Antonelli
,
+7 authors
A. Morelli
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 42912935
Portal hypertension resulting from increased intrahepatic resistance is a common complication of chronic liver diseases and a…
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Highly Cited
2001
Highly Cited
2001
An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity
S. Fiorucci
,
A. Mencarelli
,
B. Palazzetti
,
P. del Soldato
,
A. Morelli
,
L. Ignarro
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 38045984
Caspases are key mediators in liver inflammation and apoptosis. In the present study we provide evidence that a nitric oxide (NO…
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2001
2001
NCX-1000, an NO derivative of UDCA, refeases NO and protects against portal hypertension by inhibiting hepatic stellate cell contraction
S. Fiorucci
,
E. Antonelli
,
+5 authors
A. Morelli
2001
Corpus ID: 72053765
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